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Real-world data support neoadjuvant immunotherapy in dMMR/MSI CRC

Neoadjuvant immune checkpoint inhibitor (ICI) therapy demonstrates notable activity in non-metastatic deficient mismatch repair/microsatellite instability-high (dMMR/MSI) colorectal cancer (CRC), with high response rates and favourable clinical outcomes, as shown in the ongoing ambispective international observational study AGEO-NEO-MSI.

Real-world data support neoadjuvant immunotherapy in dMMR/MSI CRC

1 hour ago

Obesity tied to higher disease activity in children with JIA

2 hours ago

In children newly diagnosed with juvenile idiopathic arthritis (JIA), obesity is associated with increased disease activity and limited access to healthy food in chain grocery stores, suggests a Canada study.

Obesity tied to higher disease activity in children with JIA

2 hours ago

Nutritional anaemia raises mortality, readmission risks in patients with AECOPD

3 hours ago by

Anaemia affects nearly one in five patients hospitalized for acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and contributes to increased postdischarge mortality and readmission, a study has found. Its most common subtype is nutritional anaemia, followed by anaemia of chronic disease (ACD).

Nutritional anaemia raises mortality, readmission risks in patients with AECOPD

3 hours ago

Does prenatal Ramadan exposure affect child growth?

4 hours ago

Conflicting results over the effect of prenatal Ramadan exposure on child growth have been resolved in a recent study, which restricted samples to multifaith regions and accounts for growth faltering.

Does prenatal Ramadan exposure affect child growth?

4 hours ago

Aspirin monotherapy sufficient for venous thromboembolism prevention after arthroplasty

9 hours ago

In patients who have undergone total hip or total knee arthroplasty, postoperative treatment with aspirin alone is as good as a strategy of using rivaroxaban followed by aspirin in terms of preventing symptomatic venous thromboembolism, with no significant difference in bleeding events, according to the EPCAT III trial.

Aspirin monotherapy sufficient for venous thromboembolism prevention after arthroplasty

9 hours ago

Encapsulated rapamycin a promising chemopreventive agent in familial adenomatous polyposis

21 hours ago

In patients with familial adenomatous polyposis (FAP), treatment with encapsulated rapamycin is safe and appears to lower polyp burden, according to a phase II study.

Encapsulated rapamycin a promising chemopreventive agent in familial adenomatous polyposis

21 hours ago

Sotatercept increases exercise tolerance in PAH

a day ago

Patients with pulmonary arterial hypertension treated with sotatercept demonstrate improved exercise tolerance, driven in part by increased haemoglobin, according to a study.

Sotatercept increases exercise tolerance in PAH

a day ago

COVID-19 anticoagulation: How guidelines evolved amidst uncertainty

a day ago by

Therapeutic-dose anticoagulation has contributed to a decrease in the likelihood of organ support or death among noncritically ill hospitalized patients with COVID-19. Such experience shows how quick and rigorous approaches, when aligned, can promptly translate evidence into practice, suggests a study.

COVID-19 anticoagulation: How guidelines evolved amidst uncertainty

a day ago

Chronic eosinopenia ups risk of cardiovascular outcomes

a day ago

Adults with chronic idiopathic eosinopenia appear to be at lower long-term risk of several atherosclerotic cardiovascular outcomes, suggests a study.

Chronic eosinopenia ups risk of cardiovascular outcomes

a day ago

Dexamethasone eye drops show promise in type 1 retinopathy of prematurity

a day ago

Treatment with dexamethasone eye drops is safe and may reduce the need for invasive treatment in preemies with type 1 retinopathy of prematurity (ROP), according to the DROPROP study.

Dexamethasone eye drops show promise in type 1 retinopathy of prematurity

a day ago

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Real-world data support neoadjuvant immunotherapy in dMMR/MSI CRC

Real-world data support neoadjuvant immunotherapy in dMMR/MSI CRC

Obesity tied to higher disease activity in children with JIA

Obesity tied to higher disease activity in children with JIA

Nutritional anaemia raises mortality, readmission risks in patients with AECOPD

Nutritional anaemia raises mortality, readmission risks in patients with AECOPD

Does prenatal Ramadan exposure affect child growth?

Does prenatal Ramadan exposure affect child growth?

Aspirin monotherapy sufficient for venous thromboembolism prevention after arthroplasty

Aspirin monotherapy sufficient for venous thromboembolism prevention after arthroplasty

Encapsulated rapamycin a promising chemopreventive agent in familial adenomatous polyposis

Encapsulated rapamycin a promising chemopreventive agent in familial adenomatous polyposis

Sotatercept increases exercise tolerance in PAH

Sotatercept increases exercise tolerance in PAH

COVID-19 anticoagulation: How guidelines evolved amidst uncertainty

COVID-19 anticoagulation: How guidelines evolved amidst uncertainty

Chronic eosinopenia ups risk of cardiovascular outcomes

Chronic eosinopenia ups risk of cardiovascular outcomes

Dexamethasone eye drops show promise in type 1 retinopathy of prematurity

Dexamethasone eye drops show promise in type 1 retinopathy of prematurity