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Superior IBD control achieved with biomarker-guided therapy standard care
Biomarker-informed molecular guidance improves anti-TNF therapy outcomes in patients with inflammatory bowel disease (IBD), increasing the likelihood of achieving disease control when compared with standard “best care,” as shown in the GUIDE-IBD trial.
Superior IBD control achieved with biomarker-guided therapy standard care
26 May 2025
Full-spectrum microbiome drug for IBS with constipation clears phase II trial
The next-generation oral full-spectrum microbiome drug EBX-102-02 appears to have an acceptable safety profile in patients with irritable bowel syndrome with constipation (IBS-C) while yielding improvements in symptom severity, abdominal pain, and stool consistency, according to the results of the phase IIa TrIuMPH* study.
Full-spectrum microbiome drug for IBS with constipation clears phase II trial
25 May 2025
Linerixibat quells cholestatic itch in PBC, enabling better sleep
The ileal bile acid transporter inhibitor linerixibat provides rapid and substantial relief from cholestatic pruritus, in turn reducing associated sleep disturbances, in patients with primary biliary cholangitis (PBC), as shown in the global, phase III GLISTEN trial.
