News &amp; Updates

Certain polyfluoroalkyl substances (PFAS) in pregnant women appear to predict the trajectories of maternal weight, spanning 17 years following pregnancy, suggests a recent study.

PFAS affects weight trajectory after pregnancy

Medications for ADHD linked to blood pressure, pulse elevation

Exposure to pharmacological treatments for attention-deficit hyperactivity disorder (ADHD) appears to confer increases in blood pressure and pulse among children, teens, and adults, according to the results of a meta-analysis.

Medications for ADHD linked to blood pressure, pulse elevation

Clopidogrel outshines aspirin for secondary prevention in high-risk PCI patients

11 Apr 2025 by

In the long-term maintenance period after percutaneous coronary intervention (PCI), monotherapy with clopidogrel appears to work better than aspirin at preventing major adverse cardiac and cerebrovascular events in Asian patients at high risk of recurrent ischaemic events, as shown in the open-label SMART-CHOICE 3 trial conducted in South Korea.

Clopidogrel outshines aspirin for secondary prevention in high-risk PCI patients

Obesity linked to progressive brain structural changes

Individuals with obesity show changes in gray matter volume that stem from the reward/motivation processing regions and may expand to inhibitory control/learning memory regions, reveals a study.

Obesity linked to progressive brain structural changes

Hepatitis A vaccine may be safely administered to children on biologic therapy

Paediatric patients with autoinflammatory diseases undergoing treatment with canakinumab and tocilizumab can be safely vaccinated against hepatitis A, according to a prospective interventional study.

Hepatitis A vaccine may be safely administered to children on biologic therapy

Higher fish consumption associated with slower MS disability progression

11 Apr 2025 by

Higher fish consumption is associated with a reduced risk of disability progression in multiple sclerosis (MS), a Swedish nationwide population-based case-control study has found.

Higher fish consumption associated with slower MS disability progression

Interim data from the ongoing 7-year open-label extension (OLE) of the phase IIb X-TOLE study reflect the long-term efficacy and safety of azetukalner, an investigational, potent Kv7 potassium channel opener, for the treatment of adults with focal epilepsy.

X-TOLE OLE interim analysis shows long-term efficacy of novel agent for focal epilepsy

10 Apr 2025 by

X-TOLE OLE interim analysis shows long-term efficacy of novel agent for focal epilepsy

10 Apr 2025

BPaL regimen tied to liver injury

The overall risk of drug-induced liver injury (DILI) with the pretomanid, bedaquiline and linezolid (BPaL) regimen is lower compared with the isoniazid, rifampin, pyrazinamide and ethambutol (HRZE) regimen, a study has shown. However, the association between BPal and DILI remains significant, suggesting the need for careful monitoring during treatment.

BPaL regimen tied to liver injury

Early-onset AD implicated in paediatric uveitis

Children with early-onset atopic dermatitis (AD) face an increased risk of uveitis, as reported in a study.

Early-onset AD implicated in paediatric uveitis

Dapagliflozin after TAVI improves outcomes in elderly patients with aortic stenosis

10 Apr 2025 by

Elderly patients with aortic stenosis who received dapagliflozin after transcatheter aortic-valve implantation (TAVI) had better outcomes than those who did not receive the drug, according to the DapaTAVI* trial presented at ACC.25.

Dapagliflozin after TAVI improves outcomes in elderly patients with aortic stenosis