News &amp; Updates

Older patients on a vitamin K antagonist (VKA) derive benefits from switching to standard-dose (SD) direct-acting oral anticoagulant (DOAC) as shown by significant decreases in stroke or systemic embolism, fatal and intracranial bleeding, and death, reveals a study.

Switching to DOACs may prevent stroke, bleeding in older adults

Prenatal SSRI, SNRI exposure linked to elevated risk of PPH

Women with prenatal exposure to selective serotonin and serotonin-norepinephrine reuptake inhibitors (SSRIs and SNRIs) are at increased risk of postpartum haemorrhage (PPH), although residual confounding cannot be ruled out, as reported in a study.

Prenatal SSRI, SNRI exposure linked to elevated risk of PPH

Advancing collaboration in COVID-19 care

Held in June 2025 in Singapore, the Pfizer COVID-CONNECT Masterclass convened international experts to discuss the evolving challenges of COVID-19. Co-chaired by Dr Asok Kurup and Dr Luke Moore, this event assessed the ongoing global impact of the disease and explored evidence-based strategies across the patient journey from early identification to effective treatment.

Advancing collaboration in COVID-19 care

Oseltamivir for influenza helps reduce neuropsychiatric events

The use of oseltamivir for treating influenza episodes in children appears to lower the risk of serious neuropsychiatric events, according to a retrospective cohort study.

Oseltamivir for influenza helps reduce neuropsychiatric events

No mortality benefit with longer antibiotic prophylaxis durations in cirrhosis, upper GI bleeds

In patients with cirrhosis and upper gastrointestinal (GI) bleeds, mortality outcome does not differ between shorter and longer antibiotic prophylaxis durations, according to a systematic review and Bayesian meta-analysis.

No mortality benefit with longer antibiotic prophylaxis durations in cirrhosis, upper GI bleeds

COVID-19 and beyond: Viral infections, preparedness, and long-term impact

At the recent COVID-CONNECT Masterclass, an expert-led session explored where COVID-19 stands among common viral infections today. In a non-promotional symposium supported by Pfizer, infectious disease specialist Dr Leong Hoe Nam, Mount Elizabeth Hospital Novena, Singapore, discussed strategies for managing viral infections and surge preparedness. Complementing this, Professor David Strain from the University of Exeter Medical School, UK highlighted the enduring burden of long COVID.

COVID-19 and beyond: Viral infections, preparedness, and long-term impact

Radiotherapy plus sacituzumab govitecan feasible in metastatic breast cancer

Concurrent administration of sacituzumab govitecan and radiotherapy is well tolerated and does not lead to increased toxicity in patients with metastatic breast cancer, a study has shown.

Radiotherapy plus sacituzumab govitecan feasible in metastatic breast cancer

The E-STOP trial presented at ESHRE 2025 supports early antibiotic suspension in paediatric patients with cancer and febrile neutropenia (FN).

Study supports early antibiotic suspension in kids with cancer, febrile neutropenia

14 Aug 2025 by

Study supports early antibiotic suspension in kids with cancer, febrile neutropenia

14 Aug 2025

Semaglutide 2.4 mg: Redefining Obesity Care in Singapore

At the landmark launch of semaglutide 2.4 mg (Wegovy) in Singapore, leading experts—including Dr Tham Kwang Wei, Professor David Lau, Professor Walter Abhayaratna, and Dr Georgia Rigas—highlighted the urgent need to treat obesity as a chronic disease. The event saw record participation from over 1,300 healthcare professionals.

Semaglutide 2.4 mg: Redefining Obesity Care in Singapore