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Opioid systems influence ketamine’s antidepressant effect

Complex interactions between glutamatergic, opioidergic, and GABAergic systems modulate the antidepressant effects of ketamine on cerebral blood flow (CBF) in patients with major depressive disorder (MDD), suggests a recent study.

Opioid systems influence ketamine’s antidepressant effect

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Lithium, antidepressant prevent relapse after ECT in patients with MDD

2 hours ago

A recent Delphi-based expert consensus has released guidelines on preventing relapse after a successful electroconvulsive therapy (ECT) for patients with major depressive disorder (MDD).

Lithium, antidepressant prevent relapse after ECT in patients with MDD

2 hours ago

Lack of workplace support tied to burnout among SG health professionals

23 Jun 2026 by

A perceived lack of workplace support and less time residing in Singapore appear to contribute to the development of burnout among Allied Health Professionals (AHPs) in the post-COVID era, suggests a local study.

Lack of workplace support tied to burnout among SG health professionals

23 Jun 2026

Glucose-lowering therapy tied to reduced risk of depression in T2D

23 Jun 2026

Exposure to several glucose-lowering drugs appears to have a protective effect on the risk of depression in individuals with type 2 diabetes (T2D), according to a population-based cohort study in Hong Kong.

Glucose-lowering therapy tied to reduced risk of depression in T2D

23 Jun 2026

Psilocybin demonstrates therapeutic potential in cocaine use disorder

18 Jun 2026

In the treatment of individuals with cocaine use disorder, the use of psilocybin may help improve abstinence rates and reduce the risk of cocaine lapse over time, as shown in a study.

Psilocybin demonstrates therapeutic potential in cocaine use disorder

18 Jun 2026

Maltreated children at risk of defaulting hospital appointments

16 Jun 2026 by

Children who have been maltreated require care that routine surveillance practice do not fully meet, according to a Singapore study. Moreover, these kids are at risk of shirking their hospital appointments.

Maltreated children at risk of defaulting hospital appointments

16 Jun 2026

Rheumatology patients must undergo screening for anxiety, depression, FM: study

10 Jun 2026

A significant proportion of rheumatology patients have been diagnosed with anxiety, depression, or fibromyalgia (FM), reveals a study, noting the importance of including screening for clinical decisions at all routine encounters.

Rheumatology patients must undergo screening for anxiety, depression, FM: study

10 Jun 2026

Ecopipam halves relapse risk in paediatric Tourette syndrome

06 Jun 2026 by

The phase 3 trial of the selective dopamine D1 receptor antagonist ecopipam has demonstrated maintenace of tic suppression for up to 24 weeks and reduction in the risk of relapse of 50 percent in children with Tourette syndrome.

Ecopipam halves relapse risk in paediatric Tourette syndrome

06 Jun 2026

Lifestyle factors, comorbidities linked to difficult-to-treat rheumatoid arthritis

04 Jun 2026

Difficult-to-treat rheumatoid arthritis is associated with smoking, obesity, fibromyalgia, and depression, according to the results of a meta-analysis.

Lifestyle factors, comorbidities linked to difficult-to-treat rheumatoid arthritis

04 Jun 2026

Multimodal strategies needed to halt progression of MCI and Alzheimer’s disease

04 Jun 2026 by

Early, long-term multimodal interventions are required to halt the progression of mild cognitive impairment (MCI) and Alzheimer’s disease, according to Professor Timothy Kwok of the Division of Geriatrics, Chinese University of Hong Kong (CUHK), who spoke at AIM 2026.

Multimodal strategies needed to halt progression of MCI and Alzheimer’s disease

04 Jun 2026

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Opioid systems influence ketamine’s antidepressant effect

Opioid systems influence ketamine’s antidepressant effect

Lithium, antidepressant prevent relapse after ECT in patients with MDD

Lithium, antidepressant prevent relapse after ECT in patients with MDD

Lack of workplace support tied to burnout among SG health professionals

Lack of workplace support tied to burnout among SG health professionals

Glucose-lowering therapy tied to reduced risk of depression in T2D

Glucose-lowering therapy tied to reduced risk of depression in T2D

Psilocybin demonstrates therapeutic potential in cocaine use disorder

Psilocybin demonstrates therapeutic potential in cocaine use disorder

Maltreated children at risk of defaulting hospital appointments

Maltreated children at risk of defaulting hospital appointments

Rheumatology patients must undergo screening for anxiety, depression, FM: study

Rheumatology patients must undergo screening for anxiety, depression, FM: study

Ecopipam halves relapse risk in paediatric Tourette syndrome

Ecopipam halves relapse risk in paediatric Tourette syndrome

Lifestyle factors, comorbidities linked to difficult-to-treat rheumatoid arthritis

Lifestyle factors, comorbidities linked to difficult-to-treat rheumatoid arthritis

Multimodal strategies needed to halt progression of MCI and Alzheimer’s disease

Multimodal strategies needed to halt progression of MCI and Alzheimer’s disease