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Pembrolizumab plus chemo efficacious in advanced PSCC

02 Oct 2025

Treatment with the combination of pembrolizumab plus chemotherapy elicits response in patients with advanced penile squamous cell carcinoma (PSCC) while having a manageable safety profile, according to the phase II HERCULES trial.

Pembrolizumab plus chemo efficacious in advanced PSCC

02 Oct 2025

Original New Drug Application Approvals by US FDA (16-31 August 2025)

24 Sep 2025

New drug applications approved by US FDA as of 16-31 August 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-31 August 2025)

24 Sep 2025

Behavioural therapy as good as medication for OAB symptoms in Parkinson’s disease

16 Sep 2025 by

In the treatment of overactive bladder (OAB) in patients with Parkinson’s disease, exercise-based behavioural therapy helps reduce symptoms and bother scores and improve quality of life, similar to what is achieved with drug therapy, as shown in a study.

Behavioural therapy as good as medication for OAB symptoms in Parkinson’s disease

16 Sep 2025

Enzalutamide plus radium-223 improves rPFS in mCRPC

12 Sep 2025 by

First-line treatment with enzalutamide plus radium-223 (Ra223) results in significant improvements in radiological progression-free survival (rPFS) in patients with metastatic castration-resistant prostate cancer (mCRPC), results of the EORTC 1222/PEACE-3 trial have shown.

Enzalutamide plus radium-223 improves rPFS in mCRPC

12 Sep 2025

Chlorthalidone trumps HCTZ for stone prevention; morning dosing preferable

06 Sep 2025 by

Calcium stone formers prefer the long-acting and more effective chlorthalidone for stone prevention, reports a study. The time of administration appears irrelevant, but morning administration may be more effective in addressing higher postdinner calcium excretion.

Chlorthalidone trumps HCTZ for stone prevention; morning dosing preferable

06 Sep 2025

One functioning kidney insufficient to tell reduced renal reserve in boys with PUV

05 Sep 2025

Boys with posterior urethral valves (PUV) may find it difficult to address decreased renal reserve with only one functioning kidney on a dimercaptosuccinic acid (DMSA) scan, suggests a study.

One functioning kidney insufficient to tell reduced renal reserve in boys with PUV

05 Sep 2025

Statin exposure associated with longer OS in apalutamide-treated patients with advanced prostate cancer

28 Aug 2025 by

A study using individual patient data from the SPARTAN and TITAN randomized clinical trials has found that statin exposure was associated with superior overall survival (OS) among all patients with advanced prostate cancer (PC) who were treated with apalutamide.

Statin exposure associated with longer OS in apalutamide-treated patients with advanced prostate cancer

28 Aug 2025

GLP-1 drugs can raise testosterone levels in men

19 Aug 2025 by

The use of glucagon-like peptide 1 (GLP-1) drugs such as semaglutide, dulaglutide, and the dual agonist tirzepatide helps boost testosterone levels in men with obesity and type 2 diabetes (T2D), according to new research.

GLP-1 drugs can raise testosterone levels in men

19 Aug 2025

Does UPF intake affect semen quality in men?

13 Aug 2025 by

Consumption of ultra-processed food (UPF) does not appear to influence semen quality parameters among men attending a fertility clinic, suggests a study presented at ESHRE 2025.

Does UPF intake affect semen quality in men?

13 Aug 2025

Microplastics present in human reproductive fluids

12 Aug 2025 by

Data presented at ESHRE 2025 indicate the presence of microplastics (MPs) in follicular and seminal fluids, underscoring concerns about their potential impact on reproductive health.

Microplastics present in human reproductive fluids

12 Aug 2025

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Pembrolizumab plus chemo efficacious in advanced PSCC

Pembrolizumab plus chemo efficacious in advanced PSCC

Original New Drug Application Approvals by US FDA (16-31 August 2025)

Original New Drug Application Approvals by US FDA (16-31 August 2025)

Behavioural therapy as good as medication for OAB symptoms in Parkinson’s disease

Behavioural therapy as good as medication for OAB symptoms in Parkinson’s disease

Enzalutamide plus radium-223 improves rPFS in mCRPC

Enzalutamide plus radium-223 improves rPFS in mCRPC

Chlorthalidone trumps HCTZ for stone prevention; morning dosing preferable

Chlorthalidone trumps HCTZ for stone prevention; morning dosing preferable

One functioning kidney insufficient to tell reduced renal reserve in boys with PUV

One functioning kidney insufficient to tell reduced renal reserve in boys with PUV

Statin exposure associated with longer OS in apalutamide-treated patients with advanced prostate cancer

Statin exposure associated with longer OS in apalutamide-treated patients with advanced prostate cancer

GLP-1 drugs can raise testosterone levels in men

GLP-1 drugs can raise testosterone levels in men

Does UPF intake affect semen quality in men?

Does UPF intake affect semen quality in men?

Microplastics present in human reproductive fluids

Microplastics present in human reproductive fluids