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Bile acid reductions with odevixibat tied to improved LFTs in patients with PFIC2

16 Jul 2026 by

In individuals receiving odevixibat for progressive familial intrahepatic cholestasis 2 (PFIC2), also known as bile salt export pump (BSEP) deficiency, reductions in serum bile acid (sBA) levels correlated with improvements in key liver function tests (LFTs), according to a post hoc subgroup analysis presented at ESPGHAN 2026.

Bile acid reductions with odevixibat tied to improved LFTs in patients with PFIC2

16 Jul 2026

GLP-1 RAs confer cerebrovascular benefit in obstructive sleep apnoea

16 Jul 2026

The use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in patients with obstructive sleep apnoea (OSA) may reduce the incidence of cerebrovascular events, minimize healthcare use, and lower all-cause mortality, according to a retrospective study.

GLP-1 RAs confer cerebrovascular benefit in obstructive sleep apnoea

16 Jul 2026

Dextrose gel to prevent transitional neonatal hypoglycaemia may do more harm than good

15 Jul 2026

Administering a single dose of dextrose gel as prophylaxis against transitional neonatal hypoglycaemia does not help with the risk of neurocognitive impairment at early school age and even appears to have adverse effects on psychological well-being, according to a study.

Dextrose gel to prevent transitional neonatal hypoglycaemia may do more harm than good

15 Jul 2026

Short-cycle dosing of three-drug HIV regimen not a viable strategy for teens

15 Jul 2026 by

In adolescents living with HIV, a 5-days-on and 2-days-off dosing of antiretroviral therapy (ART) with tenofovir disoproxil fumarate, lamivudine, and dolutegravir fails to match the efficacy of continuous dosing for maintaining viral suppression, as shown in the BREATHER Plus trial conducted in Africa.

Short-cycle dosing of three-drug HIV regimen not a viable strategy for teens

15 Jul 2026

PCI delivers better angina relief in focal vs diffuse CAD

15 Jul 2026

Percutaneous coronary intervention (PCI) achieves greater symptom improvement in focal vs diffuse coronary artery disease (CAD), as shown in the ORBITA-2 study.

PCI delivers better angina relief in focal vs diffuse CAD

15 Jul 2026

Do multivitamin supplements prevent COVID-19 incidence?

15 Jul 2026 by

Daily supplementation with multivitamins offers no significant protection against the incidence of COVID-19 in older adults when compared with placebo, as shown in the COSMOS randomized trial.

Do multivitamin supplements prevent COVID-19 incidence?

15 Jul 2026

PCI outclasses OMT for chronic total coronary occlusion

15 Jul 2026

Percutaneous coronary intervention (PCI) performs better than optical medical therapy (OMT) in improving quality of life (QoL), angina frequency, and the Seattle Angina Questionnaire (SAQ) summary score in patients with a single chronic total coronary occlusion (CTO), reports a study.

PCI outclasses OMT for chronic total coronary occlusion

15 Jul 2026

Functional outcome improvements with atogepant sustained until 3 years

15 Jul 2026 by

A 156-week safety extension study presented at EAN 2026 shows the first 3-year long-term results for atogepant in the preventive treatment of migraine in individuals with chronic migraine (CM) or episodic migraine (EM) who had an insufficient response to 2–4 classes of conventional oral, non-migraine-specific preventive migraine treatments.

Functional outcome improvements with atogepant sustained until 3 years

15 Jul 2026

Dupilumab shows therapeutic potential in eosinophilic gastritis

15 Jul 2026

In the treatment of patients with eosinophilic gastritis, the use of dupilumab helps improve histological outcomes, according to the proof-of-concept, phase II DEGAS study.

Dupilumab shows therapeutic potential in eosinophilic gastritis

15 Jul 2026

Contraceptive progestogens carry meningioma risk

14 Jul 2026

Progestogens used for contraception contribute to an increased risk of meningioma, as shown in a nested case-control study.

Contraceptive progestogens carry meningioma risk

14 Jul 2026

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Bile acid reductions with odevixibat tied to improved LFTs in patients with PFIC2

Bile acid reductions with odevixibat tied to improved LFTs in patients with PFIC2

GLP-1 RAs confer cerebrovascular benefit in obstructive sleep apnoea

GLP-1 RAs confer cerebrovascular benefit in obstructive sleep apnoea

Dextrose gel to prevent transitional neonatal hypoglycaemia may do more harm than good

Dextrose gel to prevent transitional neonatal hypoglycaemia may do more harm than good

Short-cycle dosing of three-drug HIV regimen not a viable strategy for teens

Short-cycle dosing of three-drug HIV regimen not a viable strategy for teens

PCI delivers better angina relief in focal vs diffuse CAD

PCI delivers better angina relief in focal vs diffuse CAD

Do multivitamin supplements prevent COVID-19 incidence?

Do multivitamin supplements prevent COVID-19 incidence?

PCI outclasses OMT for chronic total coronary occlusion

PCI outclasses OMT for chronic total coronary occlusion

Functional outcome improvements with atogepant sustained until 3 years

Functional outcome improvements with atogepant sustained until 3 years

Dupilumab shows therapeutic potential in eosinophilic gastritis

Dupilumab shows therapeutic potential in eosinophilic gastritis

Contraceptive progestogens carry meningioma risk

Contraceptive progestogens carry meningioma risk