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Bariatric surgery, GLP1-RAs effectively reduce fat mass in obese adults

28 Jan 2026 by

Among adults with obesity, either bariatric surgery or glucagon-like peptide 1 receptor agonists (GLP-1 RAs), such as semaglutide or tirzepatide, led to substantial fat mass (FM) loss and moderate fat-free mass (FFM) loss, according to a recent study.

Bariatric surgery, GLP1-RAs effectively reduce fat mass in obese adults

28 Jan 2026

Kidney outcomes in T2D better with SGLT2i vs GLP1-RA

27 Jan 2026 by

In adults with type 2 diabetes (T2D), treatment with a sodium-glucose cotransporter-2 inhibitor (SGLT2i) confers better protection against chronic and acute kidney events compared with a glucagon-like peptide-1 receptor agonist (GLP-1RA), according to a comparative effectiveness study with a target trial emulation design.

Kidney outcomes in T2D better with SGLT2i vs GLP1-RA

27 Jan 2026

Anti-inflammatory treatment helps ease anhedonia, depressive symptoms

27 Jan 2026 by

Anti-inflammatory treatments appear useful in improving depressive symptoms and anhedonia in patients with depression who exhibit an inflammatory phenotype, results of a systematic review and meta-analysis have shown.

Anti-inflammatory treatment helps ease anhedonia, depressive symptoms

27 Jan 2026

Sublingual cyclobenzaprine fares well in fibromyalgia trial

27 Jan 2026 by

Taking sublingual cyclobenzaprine (TNX-102 SL) at bedtime relieves fibromyalgia symptoms and improves function, a phase III study suggests.

Sublingual cyclobenzaprine fares well in fibromyalgia trial

27 Jan 2026

Folic acid supplementation improves seizure, pregnancy outcomes in women with epilepsy

26 Jan 2026 by

For Chinese women with epilepsy, periconceptional folic acid intake helps minimize the incidence of seizures during pregnancy and reduce the risk of pregnancy loss, as shown in a study.

Folic acid supplementation improves seizure, pregnancy outcomes in women with epilepsy

26 Jan 2026

Body weight predicts dose reduction, discontinuation in HCC patients taking lenvatinib

26 Jan 2026

Patients with hepatocellular carcinoma (HCC) weighing <55 kg who initiate a full dose of lenvatinib tend to lose weight or discontinue treatment, reports a study.

Body weight predicts dose reduction, discontinuation in HCC patients taking lenvatinib

26 Jan 2026

Study supports neurodevelopmental safety of maternal paracetamol use

26 Jan 2026 by

A systematic review and meta-analysis support the safety of paracetamol on child neurodevelopment when used appropriately during pregnancy.

Study supports neurodevelopmental safety of maternal paracetamol use

26 Jan 2026

Berberine of little benefit in individuals with obesity and MASLD

26 Jan 2026

Treatment with berberine in diabetes-free individuals with obesity and metabolic dysfunction–associated steatotic liver disease (MASLD) is safe but falls short of reducing visceral adipose tissue (VAT) and liver fat content, as reported in a study.

Berberine of little benefit in individuals with obesity and MASLD

26 Jan 2026

Aprocitentan shows worth in patients with resistant hypertension, CKD

25 Jan 2026 by

Aprocitentan appears beneficial in the treatment of patients with both resistant hypertension and chronic kidney disease (CKD), having been shown to improve blood pressure control and reduce urine albumin-to-creatinine ratio (UACR) when added to standardized background antihypertensive therapy.

Aprocitentan shows worth in patients with resistant hypertension, CKD

25 Jan 2026

Multidisciplinary care may improve HIV PEP adherence in sexual assault victims

25 Jan 2026

Initiation of postexposure prophylaxis for HIV and completion rates in paediatric sexual assault victims can be improved by implementing a structured care system that involves multidisciplinary collaboration, pioneered by paediatric infectious diseases, suggests a Turkey study.

Multidisciplinary care may improve HIV PEP adherence in sexual assault victims

25 Jan 2026

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Bariatric surgery, GLP1-RAs effectively reduce fat mass in obese adults

Bariatric surgery, GLP1-RAs effectively reduce fat mass in obese adults

Kidney outcomes in T2D better with SGLT2i vs GLP1-RA

Kidney outcomes in T2D better with SGLT2i vs GLP1-RA

Anti-inflammatory treatment helps ease anhedonia, depressive symptoms

Anti-inflammatory treatment helps ease anhedonia, depressive symptoms

Sublingual cyclobenzaprine fares well in fibromyalgia trial

Sublingual cyclobenzaprine fares well in fibromyalgia trial

Folic acid supplementation improves seizure, pregnancy outcomes in women with epilepsy

Folic acid supplementation improves seizure, pregnancy outcomes in women with epilepsy

Body weight predicts dose reduction, discontinuation in HCC patients taking lenvatinib

Body weight predicts dose reduction, discontinuation in HCC patients taking lenvatinib

Study supports neurodevelopmental safety of maternal paracetamol use

Study supports neurodevelopmental safety of maternal paracetamol use

Berberine of little benefit in individuals with obesity and MASLD

Berberine of little benefit in individuals with obesity and MASLD

Aprocitentan shows worth in patients with resistant hypertension, CKD

Aprocitentan shows worth in patients with resistant hypertension, CKD

Multidisciplinary care may improve HIV PEP adherence in sexual assault victims

Multidisciplinary care may improve HIV PEP adherence in sexual assault victims