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PORTEC-3: Adjuvant chemoradiotherapy improves 10-year OS in high-risk endometrial cancer
15 Sep 2025
byKanas Chan
Adjuvant chemoradiotherapy (CRT) improves both 10-year overall survival (OS) and recurrence-free survival (RFS) in women with high-risk endometrial cancer vs pelvic radiotherapy alone, with the most clinically relevant benefit observed in p53 abnormal cancers, according to the 10-year analysis of the phase III PORTEC-3 trial.
PORTEC-3: Adjuvant chemoradiotherapy improves 10-year OS in high-risk endometrial cancer
15 Sep 2025
Reduced apical rotation linked to functional mitral regurgitation after ST-elevation MI
14 Sep 2025
byStephen Padilla
A significant association exists between a reduced apical rotation and functional mitral regurgitation in patients with acute ST-elevation myocardial infarction (MI), suggesting a potential novel pathophysiological mechanism, reports a study.