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Methylnaltrexone no better than placebo in easing acute pancreatitis severity

12 Dec 2024

Treatment with methylnaltrexone, a peripherally acting µ-opioid receptor antagonist, does not significantly reduce the severity of acute pancreatitis (AP) relative to placebo, a study has shown.

Methylnaltrexone no better than placebo in easing acute pancreatitis severity

12 Dec 2024

Odevixibat shows rapid, sustained benefits in patients with ALGS

12 Dec 2024 by

Treatment with odevixibat led to rapid and sustained improvements in pruritus and serum bile acid (sBA) levels among patients with Alagille syndrome (ALGS), according to the ﬁnal data of the phase III ASSERT-extension (ASSERT-EXT) study presented at The Liver Meeting 2024.

Odevixibat shows rapid, sustained benefits in patients with ALGS

12 Dec 2024

Anticoagulants up risk of bleeding after ERCP

11 Dec 2024

Endoscopists may unintentionally play down the risks of antiplatelet-related postendoscopic retrograde cholangiopancreatography (ERCP) bleeding (CSPEB) based on observations of suboptimal holding before higher risk ERCP, reports a study.

Anticoagulants up risk of bleeding after ERCP

11 Dec 2024

Microbiome-based noninvasive diagnostic tool now available for IBD

10 Dec 2024 by

Researchers at the Chinese University of Hong Kong (CUHK) have developed a microbiome-based noninvasive diagnostic tool for inflammatory bowel disease (IBD), which received a silver medal at the Geneva International Exhibition of Inventions 2024.

Microbiome-based noninvasive diagnostic tool now available for IBD

10 Dec 2024

Lidocaine infusion of no help in gut function recovery after colon resection

08 Dec 2024

Perioperative administration of 2% intravenous lidocaine does not appear to have any positive impact on gut function recovery in patients who undergo elective minimally invasive colon resection, according to a study.

Lidocaine infusion of no help in gut function recovery after colon resection

08 Dec 2024

Smartphone app on par with paper instruction for colonoscopic preparation

07 Dec 2024

Individuals undergoing colonoscopy find smartphone instructions to be as effective as traditional paper instructions for bowel preparation, reports a study.

Smartphone app on par with paper instruction for colonoscopic preparation

07 Dec 2024

Colonoscopy intervals may be extended beyond 10 years for people at low CRC risk

06 Dec 2024

Negative colonoscopy screening findings appear to be associated with lower colorectal cancer (CRC) incidence and mortality for 20 years, and as such, rescreening intervals may be extended beyond the currently recommended 10 years for people with a low-risk profile, according to a study.

Colonoscopy intervals may be extended beyond 10 years for people at low CRC risk

06 Dec 2024

Original New Drug Application Approvals by US FDA (16-30 November 2024)

06 Dec 2024

New drug applications approved by US FDA as of 16-30 November 2024 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-30 November 2024)

06 Dec 2024

Pooled analysis ASSUREs seladelpar role in PBC

04 Dec 2024 by

Results of the phase III ASSURE study support seladelpar – a novel first-in-class delpar (selective peroxisome proliferator-activated receptor delta agonist) – for the treatment of primary biliary cholangitis (PBC).

Pooled analysis ASSUREs seladelpar role in PBC

04 Dec 2024

Statins confer protection against portal hypertension, mortality in cirrhosis

01 Dec 2024 by

Statins appear to be beneficial to patients with cirrhosis, being associated with reduced risks of portal hypertension and its complications as well as death, according to a study.

Statins confer protection against portal hypertension, mortality in cirrhosis

01 Dec 2024

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Methylnaltrexone no better than placebo in easing acute pancreatitis severity

Methylnaltrexone no better than placebo in easing acute pancreatitis severity

Odevixibat shows rapid, sustained benefits in patients with ALGS

Odevixibat shows rapid, sustained benefits in patients with ALGS

Anticoagulants up risk of bleeding after ERCP

Anticoagulants up risk of bleeding after ERCP

Microbiome-based noninvasive diagnostic tool now available for IBD

Microbiome-based noninvasive diagnostic tool now available for IBD

Lidocaine infusion of no help in gut function recovery after colon resection

Lidocaine infusion of no help in gut function recovery after colon resection

Smartphone app on par with paper instruction for colonoscopic preparation

Smartphone app on par with paper instruction for colonoscopic preparation

Colonoscopy intervals may be extended beyond 10 years for people at low CRC risk

Colonoscopy intervals may be extended beyond 10 years for people at low CRC risk

Original New Drug Application Approvals by US FDA (16-30 November 2024)

Original New Drug Application Approvals by US FDA (16-30 November 2024)

Pooled analysis ASSUREs seladelpar role in PBC

Pooled analysis ASSUREs seladelpar role in PBC

Statins confer protection against portal hypertension, mortality in cirrhosis

Statins confer protection against portal hypertension, mortality in cirrhosis