News &amp; Updates

A recent study in Canada has shown similar response rates to dose-intensive cyclophosphamide, etoposide, and cisplatin (DICEP) in patients with relapsed/refractory Hodgkin lymphoma (HL) and diffuse large B-cell lymphoma (DLBCL) regardless of aprepitant use.

Does aprepitant influence response to DICEP?

HK data: Clozapine may increase infection risk in schizophrenia

Clozapine is associated with a moderately increased risk of infection vs olanzapine in patients with schizophrenia in Hong Kong, with the association being notably stronger in older age groups, according to researchers from the Department of Family Medicine and Primary Care at the University of Hong Kong (HKU).

HK data: Clozapine may increase infection risk in schizophrenia

02 Sep 2025

Parathyroidectomy lowers risk of diabetes in patients with primary hyperparathyroidism

For patients with primary hyperparathyroidism, parathyroidectomy may help prevent the development of diabetes, as reported in a study.

Parathyroidectomy lowers risk of diabetes in patients with primary hyperparathyroidism

One surgery saved three lives: Bentall procedure in a woman with aortic dissection and preterm twin pregnancy

A multidisciplinary team (MDT) at Prince Wales Hospital (PWH) and the Chinese University of Hong Kong (CUHK) successfully performed an emergency Bentall procedure in a pregnant woman with acute type A aortic dissection and preterm twins. The patient survived and her healthy twins were delivered 6 weeks later.

One surgery saved three lives: Bentall procedure in a woman with aortic dissection and preterm twin pregnancy

AI sperm analysis shows potential in reducing suboptimal fertilization outcomes in assisted reproduction

A research team from the Department of Obstetrics and Gynaecology at the University of Hong Kong (HKU) has developed the world’s first artificial intelligence (AI) model that can accurately predict the fertilization potential of spermatozoa – a breakthrough that could reshape fertilization failure diagnosis and assisted reproductive treatments worldwide.

AI sperm analysis shows potential in reducing suboptimal fertilization outcomes in assisted reproduction

Metformin plus low-to-moderate FODMAP diet improves glycaemic control, BMI and gut microbiota in prediabetes

A study by the Chinese University of Hong Kong (CUHK) in collaboration with Monash University, Australia, found that combining metformin therapy with a diet containing fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAPs) in individuals with prediabetes resulted in improved glycaemic control and gut microbiome, among other benefits, with greater effects seen with moderate-FODMAP (M-M) compared with low-FODMAP (L-M) regimens.

Metformin plus low-to-moderate FODMAP diet improves glycaemic control, BMI and gut microbiota in prediabetes

Mislabelled beta-lactam antibiotic allergy linked to post-TKA joint infection, prompts allergy delabelling service

Patients labelled as allergic to penicillin or other beta-lactam antibiotics face a significantly higher risk of periprosthetic joint infection (PJI) up to 5 years following knee arthroplasty, and should be prioritized for preoperative allergy assessment, researchers from the University of Hong Kong (HKU) have found.

Mislabelled beta-lactam antibiotic allergy linked to post-TKA joint infection, prompts allergy delabelling service

Uveitis risk reduced with GLP-1RAs

Users of glucagon-like peptide-1 receptor agonists (GLP-1RAs) are at lower risk of uveitis compared with nonusers, according to a retrospective study.

Uveitis risk reduced with GLP-1RAs

CtDNA-guided surveillance catches postoperative CRC recurrences early for curative treatment

01 Sep 2025 by

For patients who have undergone curative resection for nonmetastatic colorectal cancer (CRC), performing circulating tumour DNA (ctDNA) methylation analysis during surveillance facilitates earlier detection of recurrences suitable for curative therapy, according to interim data from the phase III FIND trial.

CtDNA-guided surveillance catches postoperative CRC recurrences early for curative treatment

01 Sep 2025

Pembrolizumab prolongs real-world survival in NSCLC patients

Treatment with pembrolizumab demonstrates effectiveness in improving progression-free survival (PFS) and overall survival (OS) in real clinical practice, results of a study have shown.

Pembrolizumab prolongs real-world survival in NSCLC patients