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SGLT-2 inhibitors may provide liver-related benefits to patients with cirrhosis

09 Jul 2025 by

The use of a sodium-glucose cotransporter 2 (SGLT-2) inhibitor helps lower the incidence of serious liver events among patients with cirrhosis who are receiving diuretic therapy, according to a study.

SGLT-2 inhibitors may provide liver-related benefits to patients with cirrhosis

09 Jul 2025

Does testosterone level predict metastasis-free survival in nmCRPC?

09 Jul 2025

Maintenance serum testosterone levels ≥20 ng/dL do not appear predictive of worse metastasis-free survival (MFS) among men with testosterone <50 ng/dL on first-line therapy of nonmetastatic castration-resistant prostate cancer (nmCRPC) using novel hormonal agents, according to a study.

Does testosterone level predict metastasis-free survival in nmCRPC?

09 Jul 2025

Malays most referred patients to nephrology care in SG

09 Jul 2025 by

A Singapore study has found that patients referred for kidney disease are predominantly Malays, who tend to have higher metabolic disease burden, miss their appointments, and be referred at lower estimated glomerular filtration rate (eGFR).

Malays most referred patients to nephrology care in SG

09 Jul 2025

Defibrillation testing may be omitted in most recipients of S-ICD

09 Jul 2025

The majority of subcutaneous implantable cardioverter defibrillator (S-ICD) recipients may safely forgo defibrillation testing (DT) during implantation, suggests a study. However, selective DT may be considered in those at higher risk.

Defibrillation testing may be omitted in most recipients of S-ICD

09 Jul 2025

Oral mitapivat beneficial in the treatment of non-transfusion-dependent thalassaemia

09 Jul 2025

Mitapivat, an oral activator of pyruvate kinase, appears to increase haemoglobin concentration and improve fatigue in adults with non-transfusion-dependent (NTD) α-thalassaemia or NTD β-thalassaemia, according to the double-blind phase III ENERGIZE study.

Oral mitapivat beneficial in the treatment of non-transfusion-dependent thalassaemia

09 Jul 2025

Structured exercise after adjuvant chemotherapy for colon cancer extend overall survival

09 Jul 2025 by

A structured exercise programme offered alongside health education materials may prolong overall survival (OS) in patients with resected colon cancer who have completed adjuvant chemotherapy, according to the final results of the phase III CHALLENGE trial presented at ASCO 2025.

Structured exercise after adjuvant chemotherapy for colon cancer extend overall survival

09 Jul 2025

Trifarotene: Acne Relieve by Modern Retinoid Molecule

09 Jul 2025 by

สิวที่หลังมักถูกมองข้ามแต่มีผลกระทบต่อคุณภาพชีวิตและความมั่นใจไม่น้อยไปกว่าสิวบนใบหน้า การรักษาเน้นการใช้ยาทากลุ่ม retinoids เป็นตัวเลือกแรก โดย trifarotene เป็น retinoid รุ่นที่ 4 ออกฤทธิ์จำเพาะต่อ RAR-γ มีประสิทธิภาพสูงในการรักษาสิวทั้งบริเวณใบหน้าและลำตัวแม้ในความเข้มข้นต่ำ สามารถลดจำนวนสิวได้ตั้งแต่ 2 สัปดาห์แรก และช่วยลดรอยหลุมสิวและรอยแผลเป็นได้ดีกว่า vehicle cream แม้อาจพบอาการระคายเคืองได้ในช่วงแรก แต่จะลดลงได้เมื่อใช้อย่างต่อเนื่อง และสามารถจัดการได้ด้วยการใช้ผลิตภัณฑ์ดูแลผิวที่เหมาะสม ยา trifarotene จึงมีศักยภาพในการรักษาสิวระดับเล็กน้อยถึงปานกลาง และมีความปลอดภัยในการใช้ระยะยาว

Trifarotene: Acne Relieve by Modern Retinoid Molecule

09 Jul 2025

Pramipexole augmentation helps in treatment-resistant depression, but side effects noted

08 Jul 2025 by

Augmenting antidepressants with pramipexole substantially improves treatment-resistant depression, although it comes with some adverse effects, according to the results of a randomized controlled trial.

Pramipexole augmentation helps in treatment-resistant depression, but side effects noted

08 Jul 2025

Fibromyalgia linked to lower sexual desire in women

08 Jul 2025

Sexual desire is reduced in women with fibromyalgia, driven primarily by age, time since diagnosis, and depressive symptoms, according to a study.

Fibromyalgia linked to lower sexual desire in women

08 Jul 2025

SSRI use, depression predict worse sexual outcomes

08 Jul 2025 by

Depression and the use of SSRIs appear to significantly contribute to an individual’s sexual functioning, distress, and pleasure, according to a study.

SSRI use, depression predict worse sexual outcomes

08 Jul 2025

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SGLT-2 inhibitors may provide liver-related benefits to patients with cirrhosis

SGLT-2 inhibitors may provide liver-related benefits to patients with cirrhosis

Does testosterone level predict metastasis-free survival in nmCRPC?

Does testosterone level predict metastasis-free survival in nmCRPC?

Malays most referred patients to nephrology care in SG

Malays most referred patients to nephrology care in SG

Defibrillation testing may be omitted in most recipients of S-ICD

Defibrillation testing may be omitted in most recipients of S-ICD

Oral mitapivat beneficial in the treatment of non-transfusion-dependent thalassaemia

Oral mitapivat beneficial in the treatment of non-transfusion-dependent thalassaemia

Structured exercise after adjuvant chemotherapy for colon cancer extend overall survival

Structured exercise after adjuvant chemotherapy for colon cancer extend overall survival

Trifarotene: Acne Relieve by Modern Retinoid Molecule

Trifarotene: Acne Relieve by Modern Retinoid Molecule

Pramipexole augmentation helps in treatment-resistant depression, but side effects noted

Pramipexole augmentation helps in treatment-resistant depression, but side effects noted

Fibromyalgia linked to lower sexual desire in women

Fibromyalgia linked to lower sexual desire in women

SSRI use, depression predict worse sexual outcomes

SSRI use, depression predict worse sexual outcomes