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Histologic EoE control tied to lower chance of stricture development in children

21 Oct 2024

Children with eosinophilic esophagitis (EoE) with a period of histologic disease control and diagnosed at younger ages appear to have reduced odds of developing esophageal strictures, according to a cohort study with >10 years of follow-up.

Histologic EoE control tied to lower chance of stricture development in children

21 Oct 2024

Original New Drug Application Approvals by US FDA (16-30 September 2024)

21 Oct 2024

New drug applications approved by US FDA as of 16-30 September 2024 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-30 September 2024)

21 Oct 2024

GLP1-RA linked to lower suicide risk among teens with obesity

20 Oct 2024

In the treatment of obesity in adolescents, the incidence of suicidal ideation or attempts appears to be lower among those receiving a glucagon-like peptide 1 receptor agonist (GLP1-RA) than among those undergoing lifestyle intervention alone, according to a retrospective study.

GLP1-RA linked to lower suicide risk among teens with obesity

20 Oct 2024

Group intervention may prevent maternal obesity transmission

17 Oct 2024

A group prenatal care intervention appears beneficial in addressing several factors associated with intergenerational transmission of obesity, suggests a study in American Samoa.

Group intervention may prevent maternal obesity transmission

17 Oct 2024

Oxybutynin lowers opioid use after paediatric urologic surgery

15 Oct 2024

A single dose of oxybutynin before urologic surgery helps children with an indwelling urinary drain to reduce their use of opioid after the procedure, a study has shown.

Oxybutynin lowers opioid use after paediatric urologic surgery

15 Oct 2024

Aspirin during pregnancy may enhance cognitive function in children

14 Oct 2024

A prospective cohort study has linked prenatal use of aspirin to better neurocognitive development in offspring.

Aspirin during pregnancy may enhance cognitive function in children

14 Oct 2024

Upadacitinib superior to dupilumab in patients with moderate-to-severe AD

13 Oct 2024 by

Treatment with upadacitinib demonstrated superior efficacy in achieving near-complete skin clearance and little to no itch at 16 weeks compared with dupilumab among adolescents and adults with moderate-to-severe atopic dermatitis (AD), according to the LEVEL UP study presented at EADV 2024.

Upadacitinib superior to dupilumab in patients with moderate-to-severe AD

13 Oct 2024

As-needed ruxolitinib in children with AD: Disease control stable through 52 weeks

12 Oct 2024 by

As-needed application of ruxolitinib cream, a topically administered selective Janus kinase 1/2 inhibitor, resulted in long-term safety and disease control in children aged 2–11 years with mild-to-moderate atopic dermatitis (AD), according to updated results of the phase III TRuE-AD3 trial presented at EADV 2024.

As-needed ruxolitinib in children with AD: Disease control stable through 52 weeks

12 Oct 2024

BMI mediates link between serum Mg level, insulin resistance in children

11 Oct 2024

The negative association between serum magnesium (Mg) levels and insulin resistance (IR) among schoolchildren is partly mediated by the BMI z-score, suggests a study in Mexico.

BMI mediates link between serum Mg level, insulin resistance in children

11 Oct 2024

Long-term secukinumab safe, effective in kids with plaque psoriasis

11 Oct 2024 by

Long-term treatment with secukinumab, either at low or high dose, results in sustained efficacy and better health-related quality of life up to 4 years in children and adolescents with moderate-to-severe chronic plaque psoriasis, as shown in a phase III study presented at EADV 2024.

Long-term secukinumab safe, effective in kids with plaque psoriasis

11 Oct 2024

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Histologic EoE control tied to lower chance of stricture development in children

Histologic EoE control tied to lower chance of stricture development in children

Original New Drug Application Approvals by US FDA (16-30 September 2024)

Original New Drug Application Approvals by US FDA (16-30 September 2024)

GLP1-RA linked to lower suicide risk among teens with obesity

GLP1-RA linked to lower suicide risk among teens with obesity

Group intervention may prevent maternal obesity transmission

Group intervention may prevent maternal obesity transmission

Oxybutynin lowers opioid use after paediatric urologic surgery

Oxybutynin lowers opioid use after paediatric urologic surgery

Aspirin during pregnancy may enhance cognitive function in children

Aspirin during pregnancy may enhance cognitive function in children

Upadacitinib superior to dupilumab in patients with moderate-to-severe AD

Upadacitinib superior to dupilumab in patients with moderate-to-severe AD

As-needed ruxolitinib in children with AD: Disease control stable through 52 weeks

As-needed ruxolitinib in children with AD: Disease control stable through 52 weeks

BMI mediates link between serum Mg level, insulin resistance in children

BMI mediates link between serum Mg level, insulin resistance in children

Long-term secukinumab safe, effective in kids with plaque psoriasis

Long-term secukinumab safe, effective in kids with plaque psoriasis