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SGLT2 inhibitors confer cardiovascular, renal benefits in stage 4 CKM syndrome

In the treatment of patients with stage 4 cardiovascular–kidney–metabolic (CKM) syndrome, sodium–glucose cotransporter 2 (SGLT2) inhibitors appear to exert cardio- and renoprotective effects, as shown in a retrospective study.

SGLT2 inhibitors confer cardiovascular, renal benefits in stage 4 CKM syndrome

3 hours ago

SGLT2 inhibitors lower stroke, mortality risks in AF patients with T2DM

29 Aug 2025

Treatment with SGLT2 inhibitors appears to reduce the risks of stroke, dementia, long-standing persistent atrial fibrillation (AF), heart failure, and mortality in patients with both AF and type 2 diabetes mellitus (T2DM), suggests a recent study.

SGLT2 inhibitors lower stroke, mortality risks in AF patients with T2DM

29 Aug 2025

7,000 steps a day may be enough

29 Aug 2025 by

Walking 7,000 steps a day can offer the same health benefits as walking 10,000 steps a day, according to a comprehensive review and meta-analysis. Experts said it could be a more realistic target than the 10,000 steps, which is traditionally seen as the benchmark to reach.

7,000 steps a day may be enough

29 Aug 2025

Steroidal mineralocorticoid receptor antagonist offers no CV mortality benefit in dialysis patients

28 Aug 2025

Treatment with steroidal mineralocorticoid receptor antagonists does not appear to provide significant protection against cardiovascular mortality in patients undergoing dialysis, as shown in a systematic review and meta-analysis.

Steroidal mineralocorticoid receptor antagonist offers no CV mortality benefit in dialysis patients

28 Aug 2025

Does hyperaldosteronism drive increased salt-sensitive BP in women?

28 Aug 2025 by

Salt-sensitive blood pressure (SSBP), aldosterone response to angiotensin II, and aldosterone/plasma renin activity (PRA) ratios are all greater in women than in men, suggests a study. However, men show higher levels of basal aldosterone and its secretagogues.

Does hyperaldosteronism drive increased salt-sensitive BP in women?

28 Aug 2025

Statin exposure associated with longer OS in apalutamide-treated patients with advanced prostate cancer

28 Aug 2025 by

A study using individual patient data from the SPARTAN and TITAN randomized clinical trials has found that statin exposure was associated with superior overall survival (OS) among all patients with advanced prostate cancer (PC) who were treated with apalutamide.

Statin exposure associated with longer OS in apalutamide-treated patients with advanced prostate cancer

28 Aug 2025

TyG index linked to hypertension incidence

27 Aug 2025

The triglyceride-glucose (TyG) index can be used to predict the incidence of hypertension, according to a study involving a population-based sample of Japanese men.

TyG index linked to hypertension incidence

27 Aug 2025

Postmeal walking reduces nighttime central SBP in women

26 Aug 2025

Walking after a meal appears to have a highest impact on nighttime systolic blood pressure (SBP) and nocturnal dipping of SBP in healthy, physically inactive young women, suggest a study.

Postmeal walking reduces nighttime central SBP in women

26 Aug 2025

Sacubitril/valsartan outdoes standard therapy in BP reduction

26 Aug 2025

Combination treatment with sacubitril and valsartan demonstrates greater efficacy than standard therapy in achieving blood pressure (BP) control and BP reduction in Afro-descendant patients with resistant hypertension, reports a study.

Sacubitril/valsartan outdoes standard therapy in BP reduction

26 Aug 2025

RA patients at high risk of degenerative valvular heart disease

24 Aug 2025

Rheumatoid arthritis (RA) may be associated with an increased risk of new-onset degenerative aortic stenosis, aortic regurgitation, and mitral regurgitation, as suggested in a study.

RA patients at high risk of degenerative valvular heart disease

24 Aug 2025

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SGLT2 inhibitors confer cardiovascular, renal benefits in stage 4 CKM syndrome

SGLT2 inhibitors confer cardiovascular, renal benefits in stage 4 CKM syndrome

SGLT2 inhibitors lower stroke, mortality risks in AF patients with T2DM

SGLT2 inhibitors lower stroke, mortality risks in AF patients with T2DM

7,000 steps a day may be enough

7,000 steps a day may be enough

Steroidal mineralocorticoid receptor antagonist offers no CV mortality benefit in dialysis patients

Steroidal mineralocorticoid receptor antagonist offers no CV mortality benefit in dialysis patients

Does hyperaldosteronism drive increased salt-sensitive BP in women?

Does hyperaldosteronism drive increased salt-sensitive BP in women?

Statin exposure associated with longer OS in apalutamide-treated patients with advanced prostate cancer

Statin exposure associated with longer OS in apalutamide-treated patients with advanced prostate cancer

TyG index linked to hypertension incidence

TyG index linked to hypertension incidence

Postmeal walking reduces nighttime central SBP in women

Postmeal walking reduces nighttime central SBP in women

Sacubitril/valsartan outdoes standard therapy in BP reduction

Sacubitril/valsartan outdoes standard therapy in BP reduction

RA patients at high risk of degenerative valvular heart disease

RA patients at high risk of degenerative valvular heart disease