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Rivaroxaban superior to metoprolol for migraine in patients with PFO
11 Aug 2026
byStephen Padilla
Three antithrombotic medications (aspirin, clopidogrel, and rivaroxaban) demonstrate noninferiority to metoprolol for responder rate (RR) in patients with migraine and patent foramen ovale (PFO), a study has shown. Rivaroxaban also delivers the highest RR without increasing major bleeding events.








