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Is sildenafil neuroprotective?

14 Jul 2025 by

A systematic review and meta-analysis conducted by researchers from Singapore demonstrates an association between treatment with sildenafil, a phosphodiesterase-5 (PDE5) inhibitor, and the risk of Alzheimer's disease (AD).

Is sildenafil neuroprotective?

14 Jul 2025

Children with UI, psychiatric disorder perform poorly in school

10 Jul 2025

Urinary incontinence (UI) does not appear to affect the performance of children in school, reports a recent study.

Children with UI, psychiatric disorder perform poorly in school

10 Jul 2025

Larger prostate glands improve faster after thermal therapy

10 Jul 2025

Patients with benign prostatic hyperplasia undergoing convective water vapor thermal therapy (CWVTT) enjoy significant improvements in lower urinary tract symptoms (LUTS) across the prostate volume (PV) spectrum. Notably, medium and large glands appear to show faster improvement than small ones.

Larger prostate glands improve faster after thermal therapy

10 Jul 2025

Does testosterone level predict metastasis-free survival in nmCRPC?

09 Jul 2025

Maintenance serum testosterone levels ≥20 ng/dL do not appear predictive of worse metastasis-free survival (MFS) among men with testosterone <50 ng/dL on first-line therapy of nonmetastatic castration-resistant prostate cancer (nmCRPC) using novel hormonal agents, according to a study.

Does testosterone level predict metastasis-free survival in nmCRPC?

09 Jul 2025

AMPLITUDE: Niraparib plus AAP improves survival in mCSPC patients with gene mutations

02 Jul 2025 by

The combination of niraparib (NIRA) and abiraterone acetate plus prednisone (AAP) results in significant improvements in radiographic progression-free survival (rPFS) and time to symptomatic progression (TSP) in metastatic castration-sensitive prostate cancer (mCSPC) patients with alterations in homologous recombination repair (HRR) genes, as shown by the results of the phase III AMPLITUDE trial.

AMPLITUDE: Niraparib plus AAP improves survival in mCSPC patients with gene mutations

02 Jul 2025

Ultrasonic propulsion clears residual stone fragments in kidney

24 Jun 2025 by

More patients who underwent ultrasonic propulsion (UP), facilitated by an independent group of operators, benefit from the passage of residual kidney stone fragments and from a decreased stone burden than those who did not receive treatment, a recent trial has shown.

Ultrasonic propulsion clears residual stone fragments in kidney

24 Jun 2025

IgAN drug hits target in phase III study

23 Jun 2025 by

The selective immunoglobulin (Ig)G2 antibody sibeprenlimab reduces proteinuria in individuals with IgA nephropathy (IgAN) in an interim analysis of the phase III VISIONARY study.

IgAN drug hits target in phase III study

23 Jun 2025

Cabozantinib plus atezolizumab improves PFS in mCRPC after progression on ARPI

20 Jun 2025

In the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) with extrapelvic soft-tissue metastases that has progressed on an androgen receptor pathway inhibitor (ARPI), the combination of cabozantinib plus atezolizumab appears to prolong progression-free survival (PFS), according to data from the open-label phase 3 CONTACT-02 trial.

Cabozantinib plus atezolizumab improves PFS in mCRPC after progression on ARPI

20 Jun 2025

Glucose-lowering med shows promise for treating kidney stones in nondiabetics

17 Jun 2025 by

Treatment with the sodium-glucose cotransporter 2 (SGLT2) inhibitor empagliflozin helps improve the urinary lithogenic risk profile of nondiabetic patients with calcium and uric acid stones, as shown in the results of the randomized crossover SWEETSTONE trial.

Glucose-lowering med shows promise for treating kidney stones in nondiabetics

17 Jun 2025

Low-carb, animal fat/protein-heavy diet poses increased bladder cancer risk

12 Jun 2025 by

A low-carbohydrate diet (LCD), particularly when its fat and protein sources are predominantly animal-based, may contribute to increased risk of bladder cancer among Chinese Singaporeans, according to new research.

Low-carb, animal fat/protein-heavy diet poses increased bladder cancer risk

12 Jun 2025

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Is sildenafil neuroprotective?

Is sildenafil neuroprotective?

Children with UI, psychiatric disorder perform poorly in school

Children with UI, psychiatric disorder perform poorly in school

Larger prostate glands improve faster after thermal therapy

Larger prostate glands improve faster after thermal therapy

Does testosterone level predict metastasis-free survival in nmCRPC?

Does testosterone level predict metastasis-free survival in nmCRPC?

AMPLITUDE: Niraparib plus AAP improves survival in mCSPC patients with gene mutations

AMPLITUDE: Niraparib plus AAP improves survival in mCSPC patients with gene mutations

Ultrasonic propulsion clears residual stone fragments in kidney

Ultrasonic propulsion clears residual stone fragments in kidney

IgAN drug hits target in phase III study

IgAN drug hits target in phase III study

Cabozantinib plus atezolizumab improves PFS in mCRPC after progression on ARPI

Cabozantinib plus atezolizumab improves PFS in mCRPC after progression on ARPI

Glucose-lowering med shows promise for treating kidney stones in nondiabetics

Glucose-lowering med shows promise for treating kidney stones in nondiabetics

Low-carb, animal fat/protein-heavy diet poses increased bladder cancer risk

Low-carb, animal fat/protein-heavy diet poses increased bladder cancer risk