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FASN inhibitor for MASH with fibrosis gets a pass to phase III
The oral fatty acid synthase (FASN) inhibitor denifanstat appears to produce meaningful improvements in metabolic dysfunction-associated steatohepatitis (MASH) and stage 2–3 fibrosis, as shown in the results of a phase IIb trial.
FASN inhibitor for MASH with fibrosis gets a pass to phase III
28 Oct 2024
Insulin resistance linked to future hypertension in normotensive salt-sensitive individuals
A 10-year study has found the association of salt sensitivity with insulin resistance and endothelial dysfunction in the offspring of hypertensive salt-sensitive parents, making them susceptible to developing hypertension.
Insulin resistance linked to future hypertension in normotensive salt-sensitive individuals
28 Oct 2024
Survodutide safe to use in cirrhosis patients
Treatment with survodutide, which has previously shown its efficacy in reducing body weight and glycaemia in people with obesity or type 2 diabetes, is well tolerated by patients with compensated or decompensated cirrhosis, reports a study.
Survodutide safe to use in cirrhosis patients
27 Oct 2024
Healthy eating may hold back prostate cancer progression
Sticking to a diet that follows the American dietary guideline recommendations may forestall the potential for low-grade prostate cancer to progress to high-grade disease, as suggested in a study.