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KEYNOTE-522 final data boost pembrolizumab role in early breast cancer
Results from the phase III KEYNOTE-522 study presented at ESMO 2024 show a statistically significant and clinically meaningful improvement in overall survival (OS) with neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab compared with neoadjuvant chemo alone for previously untreated, high-risk, early-stage triple-negative breast cancer (TNBC).
KEYNOTE-522 final data boost pembrolizumab role in early breast cancer
09 Oct 2024
Intravenous PCA with hydromorphone outperforms oral morphine for severe cancer pain
In the management of severe cancer pain, intravenous patient-controlled analgesia (PCA) with hydromorphone delivers superior pain control with greater patient satisfaction as compared with conventional oral morphine, according to the phase III open-label SYLT-021 study.
Intravenous PCA with hydromorphone outperforms oral morphine for severe cancer pain
08 Oct 2024
4-year ischaemic stroke risk higher after patent foramen ovale closure
Patients with patent foramen ovale (PFO) closure have a greater risk of ischaemic stroke at 4 years than those in the general population, according to a study.
4-year ischaemic stroke risk higher after patent foramen ovale closure
08 Oct 2024
Cemiplimab improves 5-year survival in advanced NSCLC
First-line cemiplimab monotherapy continues to provide durable overall (OS) and progression-free survival (PFS) benefits at 5 years compared with chemotherapy in advanced nonsmall cell lung cancer (NSCLC) patients with PD-L1 expression ≥50 percent, according to the results of the EMPOWER-Lung 1 study presented at WCLC 2024.
Cemiplimab improves 5-year survival in advanced NSCLC
08 Oct 2024
Physical activity, SBP tied to thoracic aortic size
Hard physical activity and normotensive individuals and increasing systolic blood pressure (SBP) in those with hypertension each correlate with larger thoracic aortic size, suggests a study.
Physical activity, SBP tied to thoracic aortic size
08 Oct 2024
Viral meningitis may induce developmental delays in kids
A mild developmental delay may occur following an infection of viral meningitis in preschool children, according to a study, noting that targeted follow-up must be considered.