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Stepwise DAPT de-escalation on par with standard therapy in ACS
A stepwise dual antiplatelet therapy (DAPT) de-escalation strategy among patients with acute coronary syndrome (ACS) who could be treated by paclitaxel-coated balloons without stents demonstrates noninferiority to the standard 12-month DAPT for all net adverse clinical events, according to a study.
Stepwise DAPT de-escalation on par with standard therapy in ACS
13 Apr 2025
Adjuvant chemo does not alter QOL trajectory for CRC patients, but functional recovery a challenge
The health-related quality of life (QOL) trajectories for colorectal cancer (CRC) patients are largely similar, regardless of whether they received adjuvant chemotherapy, according to a study from Singapore. However, CRC patients who undergo adjuvant treatments commonly experience difficulties with functional recovery.
Adjuvant chemo does not alter QOL trajectory for CRC patients, but functional recovery a challenge
12 Apr 2025
X-TOLE OLE interim analysis shows long-term efficacy of novel agent for focal epilepsy
Interim data from the ongoing 7-year open-label extension (OLE) of the phase IIb X-TOLE study reflect the long-term efficacy and safety of azetukalner, an investigational, potent Kv7 potassium channel opener, for the treatment of adults with focal epilepsy.