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Maternal TDF, infant HBV vax, HBIg-free strategy prevent infant hep B
In the absence of infant hepatitis B immune globulin (HBIg), maternal tenofovir disoproxil fumarate (TDF) prophylaxis combined with infant hepatitis B virus (HBV) immunization provide sufficient protection against HBV infection in infants, findings from the iTAP-2 study suggest. However, the risk of infection was not demonstrably below 2 percent.
Maternal TDF, infant HBV vax, HBIg-free strategy prevent infant hep B
01 Apr 2025
More syphilis cases picked up with universal vs targeted ED screening
Relying on targeted screening models for syphilis in emergency departments (EDs) leaves a substantial number of active cases undetected, new research shows.
More syphilis cases picked up with universal vs targeted ED screening
24 Mar 2025
Prenatal BPG delivery: 9-day treatment interval linked to higher risk of congenital syphilis
When treating late latent syphilis during pregnancy, extending the interval between benzathine penicillin G (BPG) doses to 9 days may put newborns at risk of congenital infection relative to 6–8-day intervals, according to new research.
Prenatal BPG delivery: 9-day treatment interval linked to higher risk of congenital syphilis
23 Mar 2025
Ensitrelvir safe, effective in preventing COVID-19 in households
Treatment with ensitrelvir among household contacts (HHC) of index patients (IP) with COVID-19 within 72 h after the onset of IP symptoms demonstrates efficacy and an acceptable safety profile as postexposure prophylaxis (PEP) in SCORPIO-PEP, a phase III placebo-controlled trial.