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OLE reflects long-term efficacy, safety of mirikizumab for CD
18 Feb 2025
byAudrey Abella
Initial findings from the ongoing VIVID-2 open-label extension (OLE) study comprising week 52 endoscopic responders from the phase III VIVID-1 trial demonstrate the long-term clinical and endoscopic efficacy of the selective anti-interleukin-23p19 monoclonal antibody mirikizumab for the treatment of moderate-to-severe active Crohn’s disease (CD).
OLE reflects long-term efficacy, safety of mirikizumab for CD
18 Feb 2025
SC dose escalation restores efficacy of infliximab in IBD patients
17 Feb 2025
byStephen Padilla
Escalating the dose of subcutaneous (SC) CT-P13, a biosimilar of infliximab, from 120 to 240 mg every 2 weeks appears to bring back the efficacy of the drug in patients with inflammatory bowel disease (IBD) who no longer respond to treatment, suggests a study presented at 2025 Crohn's & Colitis Congress.