News & Updates

Adjunctive intra-arterial lytics bounce back in ANGEL-TNK, PEARL trials

Two trials presented at ISC 2025 support intra-arterial thrombolysis as an adjunct to stroke thrombectomy in patients with large-vessel occlusions (LVOs).

Foetal malformation risk high in ART-conceived pregnancies of women with epilepsy

Conception via assisted reproductive technology (ART) carries an increased risk of foetal malformation among women with epilepsy, according to a study.

เรื่องของสมอง ทำไมต้อง ‘คาร์โนซีน’ และ ‘วิตามิน บี12’

No cardiovascular signal with anti-CGRP mAbs for migraine

Migraine treatment with monoclonal antibodies (mAbs) targeting calcitonin gene-related peptide (CGRP) or its receptor does not appear to contribute to increased risk of cardiovascular disease (CVD) compared with onabotulinumtoxinA in adults, including those who are older and with disability, according to a retrospective cohort study.

Postresuscitation care of OHCA patients lacks neuroprotection

A considerable variability exists in postresuscitation care of patients with return of spontaneous circulation (ROSC) after out-of-hospital cardiac arrest (OHCA) at the emergency department (ED), which suggests gaps between recommended guidelines and clinical practice, according to a Singapore study.

Novel BXOS110 promising neuroprotective agent in acute ischaemic stroke

BXOS110, a novel PSD-95* protein inhibitor, has shown potential for improving functional outcomes in patients with acute ischaemic stroke, according to the BEST** trial presented at ISC 2025.

Experimental drug for PD well-tolerated, offers cognitive benefits

In the treatment of patients with Parkinson’s disease (PD), the muscarinic acetylcholine M1 positive allosteric modulator TAK-071 falls short of improving gait, according to the results of a phase II study. However, the drug appears to be well-tolerated and have positive effect on cognition.