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Novel RT-PCR may help detect SARS-CoV-2 mutations tied to VoC
The Spike single-nucleotide polymorphism (SNP) assay, a single-reaction multiplex real-time RT-PCR, provides fast, inexpensive, and sensitive detection of specific mutations associated with SARS-CoV-2 variants of concern (VoC), according to data presented at ID Week 2021.
Novel RT-PCR may help detect SARS-CoV-2 mutations tied to VoC
12 Oct 2021
Mild cognitive impairment common in hypertensive patients
Mild cognitive impairment (MCI) is common among patients with hypertension, reports a recent meta-analysis. Early screening is needed in this population to facilitate timely intervention.
Mild cognitive impairment common in hypertensive patients
12 Oct 2021
Obesity may predispose individuals to early-onset colorectal adenocarcinoma
Individuals with obesity are at higher risk of developing early-onset colorectal adenocarcinoma compared with their normal-weight counterparts, as reported in a study.
Obesity may predispose individuals to early-onset colorectal adenocarcinoma
12 Oct 2021
SGLT2 inhibitors help ward off asthma
Patients on sodium-glucose co-transporter (SGLT) 2 inhibitors are less likely to develop asthma compared with those on dipeptidyl peptidase (DPP)-4 inhibitors and glucagon-like peptide-1 receptor agonists (GLP-1RAs), a study has found.
SGLT2 inhibitors help ward off asthma
12 Oct 2021
Real-world data suggest enzalutamide more suitable than abiraterone for post-docetaxel mCRPC
A real-world retrospective study reports significantly longer radiological progression-free survival (rPFS) and overall survival (OS) in metastatic castration-resistant prostate cancer (mCRPC) patients treated with enzalutamide vs abiraterone acetate after previous docetaxel therapy.
Real-world data suggest enzalutamide more suitable than abiraterone for post-docetaxel mCRPC
12 Oct 2021
Households, not schools, major SARS-CoV-2 transmission route among HK children
Households, and not schools, are the major route of coronavirus disease 2019 (COVID-19) transmission for those ≤18 years of age, according to a cross-sectional study of nearly 400 Hong Kong children and youths who contracted COVID-19 in 2020.
Households, not schools, major SARS-CoV-2 transmission route among HK children
12 Oct 2021
MET amplification a predictor of response to crizotinib
A subanalysis of the ongoing phase II PROFILE 1001 study suggests that MET amplification may serve as one of the predictive biomarkers for response to crizotinib among patients with non-small-cell lung cancer (NSCLC).
MET amplification a predictor of response to crizotinib
12 Oct 2021
Aspirin slows down metabolic clock of gestation, reduces risk of pre-eclampsia
Recent research by the Chinese University of Hong Kong (CUHK) and Baylor College of Medicine discovers that aspirin’s benefit in preventing pre-eclampsia is mediated through decelerating the metabolic clock of gestation.
Aspirin slows down metabolic clock of gestation, reduces risk of pre-eclampsia
12 Oct 2021
Tamibaroterone inhalable dry powder shows broad-spectrum activity against SARS-CoV-2, MERS and H1N1
Researchers from the University of Hong Kong (HKU) have developed a dry powder formulation of tamibaroterone, which displays broad-spectrum antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Middle East respiratory syndrome coronavirus (MERS-CoV), and pandemic 2009 influenza A virus (H1N1), when delivered intranasally or through inhalation in mouse and hamster models.