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High cEPC counts tied to worse anxiety, depression in MDD patients
Elevated counts of circulating endothelial progenitor cells (cEPCs) are correlated to worse anxiety, more severe depressive symptoms, poorer cognitive performance, greater social disability, and impaired overall mental health in patients with major depressive disorder (MDD), a recent study has found.
High cEPC counts tied to worse anxiety, depression in MDD patients
28 Sep 2021
DPP-4–to–SGLT2 inhibitor switch confers multiple benefits for patients with diabetes, hypertension
In the treatment of patients with type 2 diabetes mellitus and hypertension, switching from a dipeptidyl peptidase-4 (DPP-4) inhibitor to the sodium-glucose cotransporter-2 (SGLT2) inhibitor luseogliflozin appears to have favourable effects on blood pressure (BP), circadian rhythm, and night-time systolic BP (SBP) and pulse rate (PR), according to data from the open-label LUNA trial.
DPP-4–to–SGLT2 inhibitor switch confers multiple benefits for patients with diabetes, hypertension
28 Sep 2021
NSAIDs: suitable prophylaxis after cataract surgery?
The addition of corticosteroids (ie, prednisolone) to NSAID eyedrops (ie, ketorolac) did not provide additional benefit relative to ketorolac alone or dropless surgery using a sub-Tenon capsule depot as an anti-inflammatory prophylactic regimen to prevent postoperative central macular thickening following uncomplicated cataract surgery, a Danish study suggests.
NSAIDs: suitable prophylaxis after cataract surgery?
28 Sep 2021
Side effects limit long-term therapy for primary aldosteronism
Long-term medical therapy in patients with primary aldosteronism (PA) is held back by dose-dependent side effects, according to a recent Singapore study.