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Hydroxychloroquine falls flat for RA prevention in at-risk individuals

15 Sep 2025

Treatment with hydroxychloroquine (HCQ) for 12 months does not appear to prevent the development of rheumatoid arthritis (RA) among at-risk individuals, as shown in a phase II study.

Hydroxychloroquine falls flat for RA prevention in at-risk individuals

15 Sep 2025

ALONE-AF: Safe to stop anticoagulant therapy after AF ablation for recurrence-free patients

15 Sep 2025 bởi

For individuals without documented recurrence for at least a year following catheter ablation for atrial fibrillation (AF), discontinuing oral anticoagulant therapy results in more favourable outcomes than when continued, according to the ALONE-AF trial.

ALONE-AF: Safe to stop anticoagulant therapy after AF ablation for recurrence-free patients

15 Sep 2025

GLP-1RAs look good for idiopathic intracranial hypertension

14 Sep 2025 bởi

Glucagon-like peptide 1 receptor agonists (GLP-1RAs) appear promising in the management of idiopathic intracranial hypertension, with a retrospective study showing that the drugs reduce symptom burden as well as the need for medications and invasive procedures.

GLP-1RAs look good for idiopathic intracranial hypertension

14 Sep 2025

Mepolizumab cuts exposure to OCS in severe eosinophilic asthma

14 Sep 2025

In patients with severe eosinophilic asthma, treatment with mepolizumab reduces exposure to toxic levels of oral corticosteroids (OCS) and, in turn, the incidence of associated complications, according to a real-world study.

Mepolizumab cuts exposure to OCS in severe eosinophilic asthma

14 Sep 2025

Postpartum bleeding lower with prophylactic carbetocin vs oxytocin

13 Sep 2025 bởi

First-line prophylactic treatment with carbetocin during the third stage of labour works better than oxytocin at reducing the risk of postpartum haemorrhage (PPH), according to a study from Australia.

Postpartum bleeding lower with prophylactic carbetocin vs oxytocin

13 Sep 2025

Enzalutamide plus radium-223 improves rPFS in mCRPC

12 Sep 2025 bởi

First-line treatment with enzalutamide plus radium-223 (Ra223) results in significant improvements in radiological progression-free survival (rPFS) in patients with metastatic castration-resistant prostate cancer (mCRPC), results of the EORTC 1222/PEACE-3 trial have shown.

Enzalutamide plus radium-223 improves rPFS in mCRPC

12 Sep 2025

TALENTACE supports atezolizumab + bevacizumab after TACE for HCC

12 Sep 2025 bởi

Findings from the TALENTACE trial presented at ESMO GI 2025 support the combination of atezolizumab and bevacizumab after transarterial chemoembolization (TACE) for the treatment of individuals with systemically untreated, intermediate-to-high tumour burden, unresectable hepatocellular carcinoma (HCC).

TALENTACE supports atezolizumab + bevacizumab after TACE for HCC

12 Sep 2025

Vericiguat misses endpoint in HFrEF trial

12 Sep 2025

In the treatment of patients with heart failure and reduced ejection fraction (HFrEF) and no recent worsening, the use of vericiguat falls short of reducing the risk of the composite of cardiovascular death and HF hospitalization, as shown in a phase III study.

Vericiguat misses endpoint in HFrEF trial

12 Sep 2025

Oral pharmaceutical LSD formulation beneficial in generalized anxiety disorder

11 Sep 2025 bởi

A single administration of MM120, a semisynthetic pharmaceutical formulation of lysergic acid diethylamide (LSD), helps ease symptoms in patients with moderate to severe generalized anxiety disorder (GAD), as shown in a phase IIB study.

Oral pharmaceutical LSD formulation beneficial in generalized anxiety disorder

11 Sep 2025

Adjuvant chemotherapy predicts worse DFS in endometrial cancer

11 Sep 2025

In patients with surgically unresectable endometrial cancer who underwent neoadjuvant chemoradiation (CRT) or radiation therapy (RT), adjuvant chemotherapy is associated with worse DFS but not with improved OS, reveals a recent study.

Adjuvant chemotherapy predicts worse DFS in endometrial cancer

11 Sep 2025

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Hydroxychloroquine falls flat for RA prevention in at-risk individuals

Hydroxychloroquine falls flat for RA prevention in at-risk individuals

ALONE-AF: Safe to stop anticoagulant therapy after AF ablation for recurrence-free patients

ALONE-AF: Safe to stop anticoagulant therapy after AF ablation for recurrence-free patients

GLP-1RAs look good for idiopathic intracranial hypertension

GLP-1RAs look good for idiopathic intracranial hypertension

Mepolizumab cuts exposure to OCS in severe eosinophilic asthma

Mepolizumab cuts exposure to OCS in severe eosinophilic asthma

Postpartum bleeding lower with prophylactic carbetocin vs oxytocin

Postpartum bleeding lower with prophylactic carbetocin vs oxytocin

Enzalutamide plus radium-223 improves rPFS in mCRPC

Enzalutamide plus radium-223 improves rPFS in mCRPC

TALENTACE supports atezolizumab + bevacizumab after TACE for HCC

TALENTACE supports atezolizumab + bevacizumab after TACE for HCC

Vericiguat misses endpoint in HFrEF trial

Vericiguat misses endpoint in HFrEF trial

Oral pharmaceutical LSD formulation beneficial in generalized anxiety disorder

Oral pharmaceutical LSD formulation beneficial in generalized anxiety disorder

Adjuvant chemotherapy predicts worse DFS in endometrial cancer

Adjuvant chemotherapy predicts worse DFS in endometrial cancer