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People with gallstone disease are at higher risk of inflammatory bowel disease (IBD), regardless of other traditional risk factors, according to a study.

Gallstone disease ups IBD risk

Risk-reducing surgeries tied to improved outcomes in BRCA carriers with young-onset BC

20 Jan 2025 bởi

A large global study provides evidence that risk-reducing mastectomy (RRM) and/or risk-reducing salpingo-oophorectomy (RRSO) is associated with improved survival outcomes in young women diagnosed with breast cancer (BC) at or before 40 years of age who were harbouring germline BRCA1 and/or BRCA2 pathogenic variants (PVs).

Risk-reducing surgeries tied to improved outcomes in BRCA carriers with young-onset BC

20 Jan 2025

Noncigarette tobacco products carry distinct health risks

The use of noncigarette tobacco products is associated with distinctive cardiovascular outcomes, including stroke for cigar, heart failure for pipe, and total cardiovascular disease (CVD) for smokeless tobacco, as shown in a study.

Noncigarette tobacco products carry distinct health risks

Novel drug for moderate-to-severe UC yields quality-of-life benefits

20 Jan 2025 bởi

RO7790121, an antibody against tumour necrosis factor-like ligand 1A (Anti-TL1A), helps improve the health-related quality of life (HR-QoL) for patients with moderately to severely active ulcerative colitis (UC), as shown in the phase IIb TUSCANY-2 trial.

Novel drug for moderate-to-severe UC yields quality-of-life benefits

Anti-TNFs may reduce GDM risk in pregnant women with IBD

Pregnant women with inflammatory bowel disease (IBD) who used antitumour necrosis factor (anti-TNF) therapy are at reduced risk of developing gestational diabetes mellitus (GDM), reports a study.

Anti-TNFs may reduce GDM risk in pregnant women with IBD

Hormone therapy poses no glioma risk

Users of hormone therapy do not appear to be at increased risk of glioma, according to a study.

Hormone therapy poses no glioma risk

Labour pain, complications drive early breastfeeding cessation

18 Jan 2025 bởi

Among breastfeeding mums in Singapore, those who had obstetric complications and experienced more pain during labour tend to stop sooner than the recommended 6 months, according to a study.

Labour pain, complications drive early breastfeeding cessation

Making the case for paediatric one-day admission in SG

18 Jan 2025 bởi

One-day admissions for paediatric patients may offer ways to help prevent hospital congestion, suggests a Singapore study.

Making the case for paediatric one-day admission in SG

Twice-yearly depemokimab tied to fewer severe asthma exacerbations

In the treatment of severe asthma with an eosinophilic phenotype, 6-month dosing intervals of depemokimab appears to reduce the rate of exacerbations, as shown in a phase IIIA study.

Twice-yearly depemokimab tied to fewer severe asthma exacerbations