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Pulse steroid therapy tied to bone turnover marker suppression, but not BMD loss

06 Jul 2026 bởi

Pulse intravenous methylprednisolone does not induce short-term loss of lumbar spine or hip bone mineral density (BMD), reports a Singapore study. However, it does suppress bone turnover markers, suggesting early effects on bone remodelling that are not captured by BMD alone.

Pulse steroid therapy tied to bone turnover marker suppression, but not BMD loss

06 Jul 2026

Anticoagulants up risk of bleeding after esophageal dilation procedure

06 Jul 2026

Patients taking anticoagulant medications at the time of esophageal dilation are at increased risk of experiencing gastrointestinal bleeding after the procedure, suggests a study.

Anticoagulants up risk of bleeding after esophageal dilation procedure

06 Jul 2026

Pooled analysis validates iptacopan safety for PNH

06 Jul 2026 bởi

A pooled analysis presented at EHA 2026 demonstrates the long-term safety of the oral proximal complement inhibitor iptacopan in the treatment of paroxysmal nocturnal haemoglobinuria (PNH).

Pooled analysis validates iptacopan safety for PNH

06 Jul 2026

High-dose cannabidiol offers relief in patients with chronic neuropathic pain

06 Jul 2026

In the treatment of patients with chronic neuropathic pain, high-dose cannabidiol (CBD) helps reduce pain intensity and is well-tolerated, according to a crossover study.

High-dose cannabidiol offers relief in patients with chronic neuropathic pain

06 Jul 2026

Upfront immunosuppression regimen improves survival in acquired haemophilia A

05 Jul 2026 bởi

In the first-line treatment of acquired haemophilia A (AHA), the use of an intravenous (IV) pulse-dose immunosuppression regimen that combines cyclophosphamide, dexamethasone, and rituximab appears to result in faster remission and improved survival compared with traditional oral sequential prednisone-based regimens, according to a study.

Upfront immunosuppression regimen improves survival in acquired haemophilia A

05 Jul 2026

Novel oral small-molecule PCSK9 inhibitor shows promise in hypercholesterolemia

04 Jul 2026

In the treatment of hypercholesterolemia, the investigational oral small-molecule PCSK9 inhibitor laroprovstat appears well tolerated and may help reduce low-density lipoprotein cholesterol (LDL-C) levels when used in combination with rosuvastatin, according to a phase I study.

Novel oral small-molecule PCSK9 inhibitor shows promise in hypercholesterolemia

04 Jul 2026

CCB outperforms beta-blocker for managing hypertension in HFpEF

03 Jul 2026 bởi

The oral dihydropyridine calcium channel blocker (CCB) amlodipine appears more beneficial than the beta-blocker metoprolol for managing hypertension in patients with heart failure with preserved ejection fraction (HFpEF), with greater effects on blood pressure (BP) control and exercise capacity, as shown in a randomized crossover trial.

CCB outperforms beta-blocker for managing hypertension in HFpEF

03 Jul 2026

How does baricitinib compare in RA patients at risk of VTE?

03 Jul 2026 bởi

Treatment with baricitinib misses the noninferiority mark against tumour necrosis factor inhibitors (TNFi) in active rheumatoid arthritis (RA) patients at risk for venous thromboembolism (VTE) with high baseline disease activity, reports a study.

How does baricitinib compare in RA patients at risk of VTE?

03 Jul 2026

Novel extended-release tablet superior to febuxostat at reducing SUA levels

03 Jul 2026 bởi

An extended-release formulation, HR091506, performs better than febuxostat immediate release in lowering urate levels in patients with gout and hyperuricaemia, as shown in a phase III trial.

Novel extended-release tablet superior to febuxostat at reducing SUA levels

03 Jul 2026

$Substance use, poverty, race predictive of orbital, facial fractures$

Substance use, poverty, race predictive of orbital, facial fractures

03 Jul 2026

Social determinants of health (SDOH) are significantly associated with maxillofacial trauma, suggests a US study. These SDOH factors include substance use, unhoused status, and poverty, among others

Substance use, poverty, race predictive of orbital, facial fractures

03 Jul 2026

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Pulse steroid therapy tied to bone turnover marker suppression, but not BMD loss

Pulse steroid therapy tied to bone turnover marker suppression, but not BMD loss

Anticoagulants up risk of bleeding after esophageal dilation procedure

Anticoagulants up risk of bleeding after esophageal dilation procedure

Pooled analysis validates iptacopan safety for PNH

Pooled analysis validates iptacopan safety for PNH

High-dose cannabidiol offers relief in patients with chronic neuropathic pain

High-dose cannabidiol offers relief in patients with chronic neuropathic pain

Upfront immunosuppression regimen improves survival in acquired haemophilia A

Upfront immunosuppression regimen improves survival in acquired haemophilia A

Novel oral small-molecule PCSK9 inhibitor shows promise in hypercholesterolemia

Novel oral small-molecule PCSK9 inhibitor shows promise in hypercholesterolemia

CCB outperforms beta-blocker for managing hypertension in HFpEF

CCB outperforms beta-blocker for managing hypertension in HFpEF

How does baricitinib compare in RA patients at risk of VTE?

How does baricitinib compare in RA patients at risk of VTE?

Novel extended-release tablet superior to febuxostat at reducing SUA levels

Novel extended-release tablet superior to febuxostat at reducing SUA levels

Substance use, poverty, race predictive of orbital, facial fractures

Substance use, poverty, race predictive of orbital, facial fractures