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Maternal asthma may raise congenital heart defect risk in offspring
Maternal asthma may raise congenital heart defect risk in offspring
15 Jan 2026 bởiStephen Padilla

Asthma and allergic tendency in mothers appear to elevate the risk of congenital heart defect (CHD) in their children, suggests a study, noting that nonallergic asthma also contributes to such risk.

Maternal asthma may raise congenital heart defect risk in offspring
15 Jan 2026
EPIK-B5 supports alpelisib plus fulvestrant for HR+, HER2– ABC
EPIK-B5 supports alpelisib plus fulvestrant for HR+, HER2– ABC
15 Jan 2026 bởiAudrey Abella

In the phase III EPIK-B5 study, adding alpelisib, an α-specific PI3K inhibitor, to fulvestrant improves progression-free survival (PFS) in men and postmenopausal women with HR+, HER2− advanced breast cancer (ABC) harbouring a PIK3CA mutation who have progressed on or after treatment with an aromatase inhibitor (AI) and a CDK4/6 inhibitor (CDK4/6i).

EPIK-B5 supports alpelisib plus fulvestrant for HR+, HER2– ABC
15 Jan 2026