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The use of cenobamate across different treatment lines proves effective at reducing seizures in patients with epilepsy, according to real-world data.

Cenobamate for epilepsy effective across multiple treatment lines

SGLT2i helps prevent cardiovascular events in diabetes patients with acute MI

Early treatment with sodium-glucose cotransporter 2 inhibitors (SGLT2i) is associated with a lower cardiovascular risk among diabetes patients with acute myocardial infarction (MI), reports a study.

SGLT2i helps prevent cardiovascular events in diabetes patients with acute MI

Toripalimab plus gemcitabine-cisplatin shows promise as neoadjuvant treatment in MIBC

Combining toripalimab with gemcitabine and cisplatin chemotherapy is safe and efficacious in patients with muscle-invasive bladder cancer (MIBC), demonstrating its potential as a neoadjuvant treatment (NAT) in a phase II clinical trial.

Toripalimab plus gemcitabine-cisplatin shows promise as neoadjuvant treatment in MIBC

Elevated baseline LH, prior ADT predict poor response to clomiphene citrate

Higher luteinizing hormone (LH) at baseline and a history of prior androgen-deprivation therapy (ADT) are associated with worse response to clomiphene citrate (CC) therapy in men with low testosterone, a study has shown.

Elevated baseline LH, prior ADT predict poor response to clomiphene citrate

Glucocorticoid treatment carries risk of adverse psychiatric outcomes

28 Jun 2026

Treatment with oral glucocorticoids may contribute to elevated risks of adverse psychiatric outcomes, including the onset and relapse of common psychiatric disorders, as shown in a population-based cohort study.

Glucocorticoid treatment carries risk of adverse psychiatric outcomes

28 Jun 2026

Combined oral contraceptive use increases susceptibility to emotional eating

Users of combined oral contraceptives (COCs) are at increased risk of emotional eating, as reported in a study.

Combined oral contraceptive use increases susceptibility to emotional eating

Antibiotic stewardship improves acute appendicitis outcomes in children

27 Jun 2026 bởi

An antimicrobial stewardship intervention to reduce the use of piperacillin–tazobactam in children with acute appendicitis has been shown to result in improved clinical outcomes.

Antibiotic stewardship improves acute appendicitis outcomes in children

Orforglipron promotes weight loss across all menopausal stages

27 Jun 2026 bởi

Once-daily treatment with the highest orforglipron dose is associated with significant reductions in body weight and waist circumference at week 72 in women with obesity or overweight, regardless of menopausal status, according to a post hoc analysis of the phase III ATTAIN-1 and -2 trials presented at ADA 2026.

Orforglipron promotes weight loss across all menopausal stages