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Original New Drug Application Approvals by US FDA (16-31 March 2025)

New drug applications approved by US FDA as of 16-31 March 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Women more likely than men to receive high-intensity statins for secondary prevention post-CABG

Women are more likely than men to fill prescriptions for statin, particularly high-intensity dosages, after undergoing coronary artery bypass surgery (CABG), with statin therapy equally effective at reducing mortality for both sexes, according to a study.

Vaccination crucial to integrated dengue prevention and control in SEA

Southeast Asia (SEA) is one of the hotspots for dengue infections, with Indonesia and Thailand among the highly endemic countries. At a Takeda-sponsored symposium held during the 2nd APIC-ADVA Asia Pacific Summit on Infectious Diseases and Immunization in Singapore, experts focused on vaccination as an integral component of a holistic dengue prevention and control strategy in SEA.

*The editorial below is supported by Takeda Pharmaceuticals International AG Singapore Branch and is intended solely for informational purposes. Takeda has not influenced or contributed to the editorial content. While Takeda has provided financial support for the editorial, Takeda shall not be held responsible or liable for any errors, omissions, or inaccuracies in such information.

Amlodipine makes up half of CCB overdoses; verapamil, diltiazem remain most toxic

Among the cases of calcium channel blocker (CCB) overdose, dihydropyridines are the most common, with amlodipine accounting for nearly half. On the other hand, more severe toxicities occur with the use of verapamil and diltiazem.

Air pollution exposure a risk factor for epilepsy

Exposure to increased levels of fine particulate matter (PM2.5) and ground-level ozone (O3) has been linked to an increased risk of new-onset epilepsy in a recent study.

HIV-exposed, uninfected children show growth lag

Children exposed to HIV but uninfected appear to have an initial growth deficit at birth that persists for at least the first 24 months of life, according to a meta-analysis.

Brisk walking may protect against erectile dysfunction

Men who do brisk walking are less likely to suffer from erectile dysfunction (ED), suggests a study that shows an inverse relationship between walking pace and ED risk.