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Novel BTK inhibitor on par with ocrelizumab in reducing disability progression in PPMS
17 Jul 2026
bởiStephen Padilla
The investigational Bruton’s tyrosine kinase (BTK) inhibitor fenebrutinib demonstrates its noninferiority to ocrelizumab in reducing the risk of disability progression in patients with primary progressive multiple sclerosis (PPMS) in the phase III FENtrepid study.
Novel BTK inhibitor on par with ocrelizumab in reducing disability progression in PPMS
17 Jul 2026
Bile acid reductions with odevixibat tied to improved LFTs in patients with PFIC2
16 Jul 2026
bởiAudrey Abella
In individuals receiving odevixibat for progressive familial intrahepatic cholestasis 2 (PFIC2), also known as bile salt export pump (BSEP) deficiency, reductions in serum bile acid (sBA) levels correlated with improvements in key liver function tests (LFTs), according to a post hoc subgroup analysis presented at ESPGHAN 2026.







