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Anxiety, adaptive behaviours modify link between dysphagia, HDA in EoE

12 Aug 2025

Higher esophageal anxiety, use of adaptive behaviours, and hypervigilance are common among patients with active eosinophilic esophagitis (EoE), representing clinical markers of histological disease activity (HDA), a study has found.

Anxiety, adaptive behaviours modify link between dysphagia, HDA in EoE

12 Aug 2025

Vorasidenib prevents seizures in mIDH1/2 gliomas

12 Aug 2025 bởi

Patients with grade 2 isocitrate dehydrogenase 1 or 2 mutant (mIDH1/2) gliomas receiving vorasidenib experience fewer seizure activities than those on placebo, as shown by the results of the INDIGO study.

Vorasidenib prevents seizures in mIDH1/2 gliomas

12 Aug 2025

Eptinezumab eases migraine, medication-overuse headache

12 Aug 2025 bởi

Two separate randomized controlled trials (SUNRISE and RESOLUTION) have shown the superiority of eptinezumab over placebo in a predominantly Asian migraine population and in patients with chronic migraine (CM) and medication-overuse headache (MOH).

Eptinezumab eases migraine, medication-overuse headache

12 Aug 2025

Microplastics present in human reproductive fluids

12 Aug 2025 bởi

Data presented at ESHRE 2025 indicate the presence of microplastics (MPs) in follicular and seminal fluids, underscoring concerns about their potential impact on reproductive health.

Microplastics present in human reproductive fluids

12 Aug 2025

Underweight linked to increased osteoporosis risk

12 Aug 2025

Being underweight puts adolescents at risk of osteoporosis in adulthood, and this risk further increases in those who remain underweight in their adult life, according to a retrospective study.

Underweight linked to increased osteoporosis risk

12 Aug 2025

Switching to dual ART noninferior to continuing triple ART in maintaining viral suppression among PLWH

12 Aug 2025 bởi

Switching to maintenance dual antiretroviral therapy (ART) with DTG+3TC* or ATV/r+3TC** was noninferior to continuing triple current ART with TDF+3TC+EFV*** or DTG+3TC+TDF⁺ in maintaining virologic suppression for up to 96 weeks among people living with HIV (PLWH), according to the MODERATO trial presented at IAS 2025.

Switching to dual ART noninferior to continuing triple ART in maintaining viral suppression among PLWH

12 Aug 2025

Diet linked to cognitive function in older adults via gut microbiota

12 Aug 2025 bởi

Greater adherence to dietary patterns that are beneficial to gut microbiota is associated with better cognitive function in older adults, according to data from the US National Health and Nutrition Examination Survey (NHANES). When these findings were validated in an independent Hong Kong osteoporosis cohort, higher dietary fibre intake significantly correlated with higher cognitive scores in older adults in Hong Kong.

Diet linked to cognitive function in older adults via gut microbiota

12 Aug 2025

Periconceptional GLP-1RA exposure safety varies on indication for use

11 Aug 2025 bởi

Exposure to glucagon-like peptide 1 receptor agonists (GLP-1RAs) during pregnancy poses a modest increase in the risk of preterm birth in the context of diabetes treatment, but there is no evidence of increased obstetric complications when the drugs are exclusively used for weight management, according to new research.

Periconceptional GLP-1RA exposure safety varies on indication for use

11 Aug 2025

MASLD severity tied to poor cognitive function, HRQoL in patients with obesity

11 Aug 2025

Greater severity in metabolic dysfunction-associated steatotic liver disease (MASLD) may impair cognitive function and health-related quality of life (HRQoL) in patients with overweight or obesity, suggests a study.

MASLD severity tied to poor cognitive function, HRQoL in patients with obesity

11 Aug 2025

HBV vaccination, HIV PEP compliance low among young sexual assault victims

11 Aug 2025 bởi

Many paediatric sexual assault victims do not receive hepatitis B virus (HBV) postexposure vaccination and have low compliance to HIV postexposure prophylaxis (PEP), reveals a study in Singapore.

HBV vaccination, HIV PEP compliance low among young sexual assault victims

11 Aug 2025

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Anxiety, adaptive behaviours modify link between dysphagia, HDA in EoE

Anxiety, adaptive behaviours modify link between dysphagia, HDA in EoE

Vorasidenib prevents seizures in mIDH1/2 gliomas

Vorasidenib prevents seizures in mIDH1/2 gliomas

Eptinezumab eases migraine, medication-overuse headache

Eptinezumab eases migraine, medication-overuse headache

Microplastics present in human reproductive fluids

Microplastics present in human reproductive fluids

Underweight linked to increased osteoporosis risk

Underweight linked to increased osteoporosis risk

Switching to dual ART noninferior to continuing triple ART in maintaining viral suppression among PLWH

Switching to dual ART noninferior to continuing triple ART in maintaining viral suppression among PLWH

Diet linked to cognitive function in older adults via gut microbiota

Diet linked to cognitive function in older adults via gut microbiota

Periconceptional GLP-1RA exposure safety varies on indication for use

Periconceptional GLP-1RA exposure safety varies on indication for use

MASLD severity tied to poor cognitive function, HRQoL in patients with obesity

MASLD severity tied to poor cognitive function, HRQoL in patients with obesity

HBV vaccination, HIV PEP compliance low among young sexual assault victims

HBV vaccination, HIV PEP compliance low among young sexual assault victims