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Delayed postoperative radiation tied to higher recurrence, death in MCC

23 Jan 2024

Delays in postoperative radiation therapy (PORT) may lead to increased locoregional recurrence (LRR), usually occurring beyond the radiation field, among patients with Merkel cell carcinoma (MCC), as shown in a recent study.

Delayed postoperative radiation tied to higher recurrence, death in MCC

23 Jan 2024

Berdazimer gel reduces molluscum contagiosum lesions in children

22 Jan 2024 bởi

An analysis of three randomized controlled trials (RCTs) has shown the efficacy and safety of berdazimer gel, a topical, antiviral, nitric oxide-releasing medication, in the treatment of molluscum contagiosum (MC) lesions in patients aged 6 months and older. Application-site pain and erythema are the most common adverse events (AEs) related to treatment.

Berdazimer gel reduces molluscum contagiosum lesions in children

22 Jan 2024

Original New Drug Application Approvals by US FDA (01-15 January 2024)

18 Jan 2024

New drug applications approved by US FDA as of 01-15 January 2024 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (01-15 January 2024)

18 Jan 2024

Original New Drug Application Approvals by US FDA (16-31 December 2023)

03 Jan 2024

New drug applications approved by US FDA as of 16-31 December 2023 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-31 December 2023)

03 Jan 2024

Acitretin plus triamcinolone treats oral lichen planus better than triamcinolone monotherapy

21 Dec 2023

The combination of oral acitretin plus topical triamcinolone acetonide (TAC) appears to have superior efficacy than TAC alone in the treatment of patients with oral lichen planus, as shown in a study.

Acitretin plus triamcinolone treats oral lichen planus better than triamcinolone monotherapy

21 Dec 2023

Long-term risankizumab safe, effective in moderate-to-severe plaque psoriasis

20 Dec 2023 bởi

Treatment with risankizumab in the long term shows lasting efficacy against moderate-to-severe plaque psoriasis and has good tolerability, according to the LIMMitless study.

Long-term risankizumab safe, effective in moderate-to-severe plaque psoriasis

20 Dec 2023

Original New Drug Application Approvals by US FDA (01-15 December 2023)

18 Dec 2023

New drug applications approved by US FDA as of 01-15 December 2023 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (01-15 December 2023)

18 Dec 2023

Low-dose methotrexate may pose serious adverse event risk for older adults with CKD

05 Dec 2023 bởi

For older adults with chronic kidney disease (CKD) who are initiating a disease-modifying antirheumatic drug (DMARD), low-dose methotrexate appears to be associated with a heightened 90-day risk of serious adverse events compared with hydroxychloroquine, as shown in a study.

Low-dose methotrexate may pose serious adverse event risk for older adults with CKD

05 Dec 2023

Remibrutinib improves CSU symptoms in phase III trials

05 Dec 2023 bởi

Treatment with the investigational, oral Bruton’s tyrosine kinase (BTK) inhibitor remibrutinib improves symptoms in patients with chronic spontaneous urticaria (CSU) inadequately controlled on antihistamines, the phase III REMIX-1 and -2 studies have shown.

Remibrutinib improves CSU symptoms in phase III trials

05 Dec 2023

Givosiran delivers safe, sustained improvements in acute hepatic porphyria

28 Nov 2023 bởi

Long-term monthly treatment with givosiran has good tolerability and offers continuous improvements to patients with acute hepatic porphyria (AHP), results of the phase III ENVISION trial have shown.

Givosiran delivers safe, sustained improvements in acute hepatic porphyria

28 Nov 2023

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Delayed postoperative radiation tied to higher recurrence, death in MCC

Delayed postoperative radiation tied to higher recurrence, death in MCC

Berdazimer gel reduces molluscum contagiosum lesions in children

Berdazimer gel reduces molluscum contagiosum lesions in children

Original New Drug Application Approvals by US FDA (01-15 January 2024)

Original New Drug Application Approvals by US FDA (01-15 January 2024)

Original New Drug Application Approvals by US FDA (16-31 December 2023)

Original New Drug Application Approvals by US FDA (16-31 December 2023)

Acitretin plus triamcinolone treats oral lichen planus better than triamcinolone monotherapy

Acitretin plus triamcinolone treats oral lichen planus better than triamcinolone monotherapy

Long-term risankizumab safe, effective in moderate-to-severe plaque psoriasis

Long-term risankizumab safe, effective in moderate-to-severe plaque psoriasis

Original New Drug Application Approvals by US FDA (01-15 December 2023)

Original New Drug Application Approvals by US FDA (01-15 December 2023)

Low-dose methotrexate may pose serious adverse event risk for older adults with CKD

Low-dose methotrexate may pose serious adverse event risk for older adults with CKD

Remibrutinib improves CSU symptoms in phase III trials

Remibrutinib improves CSU symptoms in phase III trials

Givosiran delivers safe, sustained improvements in acute hepatic porphyria

Givosiran delivers safe, sustained improvements in acute hepatic porphyria