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Inclisiran confers LDL–C-lowering benefit in adolescents with HoFH

29 Jun 2025

In adolescents with homozygous familial hypercholesterolemia (HoFH), treatment with inclisiran appears to be safe and efficacious for reducing low-density lipoprotein cholesterol (LDL-C) levels, according to the results of the first part of the phase III ORION-13* trial.

Inclisiran confers LDL–C-lowering benefit in adolescents with HoFH

29 Jun 2025

Infant psychomotor development not harmed by biologic exposure in utero, during breastfeeding

28 Jun 2025

Exposure to biologics for inflammatory bowel disease (IBD) in utero or during breastfeeding does not appear to impair psychomotor development in infants, according to a study.

Infant psychomotor development not harmed by biologic exposure in utero, during breastfeeding

28 Jun 2025

Narcolepsy tied to increased risk of subclinical CVD

28 Jun 2025

Individuals with narcolepsy, including children, appear to have an elevated risk of subclinical cardiovascular disease (CVD), according to a retrospective study.

Narcolepsy tied to increased risk of subclinical CVD

28 Jun 2025

Children suffer anxiety while in isolation during COVID-19 pandemic

25 Jun 2025 bởi

Hospital isolation for COVID-19 caused heightened anxiety in families, particularly children, during the early phase of the pandemic, according to a Singapore study.

Children suffer anxiety while in isolation during COVID-19 pandemic

25 Jun 2025

Review underpins poor functional outcomes in AYAs with bony sarcomas

25 Jun 2025 bởi

In a scoping review examining the functional outcomes of individuals with bony sarcomas, adolescent and young adult oncology (AYAO) patients seem to fare worse than their healthy counterparts and bony sarcoma patients from various age groups.

Review underpins poor functional outcomes in AYAs with bony sarcomas

25 Jun 2025

Paternal mental distress may affect child development

23 Jun 2025

The perinatal mental distress experienced by a father appears to have a negative effect on the offspring’s developmental outcomes from infancy through adolescence, according to a meta-analysis.

Paternal mental distress may affect child development

23 Jun 2025

Original New Drug Application Approvals by US FDA (16-31 May 2025)

23 Jun 2025

New drug applications approved by US FDA as of 16-31 May 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-31 May 2025)

23 Jun 2025

Chronic medical, psychiatric comorbidities common in paediatric hidradenitis suppurativa

21 Jun 2025

Children with hidradenitis suppurativa (HS) are prone to a number of metabolic, endocrinologic, dermatologic, psychiatric, and genetic comorbidities, including obesity, anxiety, and acne vulgaris, according to the findings of a systematic review and meta-analysis.

Chronic medical, psychiatric comorbidities common in paediatric hidradenitis suppurativa

21 Jun 2025

Long-term odevixibat shows sustained benefits in ALGS

20 Jun 2025 bởi

Long-term treatment with odevixibat led to sustained improvements in pruritus scores and reductions in serum bile acid (sBA) levels among patients with Alagille syndrome (ALGS), based on a pooled analysis of the phase III ASSERT and ASSERT-EXT studies presented at ESPGHAN 2025.

Long-term odevixibat shows sustained benefits in ALGS

20 Jun 2025

Study ties energy drink intake to unhealthy lifestyle in young individuals

19 Jun 2025 bởi

A study presented at ESPGHAN 2025 reports that schoolchildren who consume energy drinks have unhealthier lifestyles and a different cardiovascular risk profile than their counterparts who do not or rarely consume energy drinks.

Study ties energy drink intake to unhealthy lifestyle in young individuals

19 Jun 2025

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Inclisiran confers LDL–C-lowering benefit in adolescents with HoFH

Inclisiran confers LDL–C-lowering benefit in adolescents with HoFH

Infant psychomotor development not harmed by biologic exposure in utero, during breastfeeding

Infant psychomotor development not harmed by biologic exposure in utero, during breastfeeding

Narcolepsy tied to increased risk of subclinical CVD

Narcolepsy tied to increased risk of subclinical CVD

Children suffer anxiety while in isolation during COVID-19 pandemic

Children suffer anxiety while in isolation during COVID-19 pandemic

Review underpins poor functional outcomes in AYAs with bony sarcomas

Review underpins poor functional outcomes in AYAs with bony sarcomas

Paternal mental distress may affect child development

Paternal mental distress may affect child development

Original New Drug Application Approvals by US FDA (16-31 May 2025)

Original New Drug Application Approvals by US FDA (16-31 May 2025)

Chronic medical, psychiatric comorbidities common in paediatric hidradenitis suppurativa

Chronic medical, psychiatric comorbidities common in paediatric hidradenitis suppurativa

Long-term odevixibat shows sustained benefits in ALGS

Long-term odevixibat shows sustained benefits in ALGS

Study ties energy drink intake to unhealthy lifestyle in young individuals

Study ties energy drink intake to unhealthy lifestyle in young individuals