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Pembrolizumab plus gemcitabine/cisplatin improves survival in metastatic biliary tract cancer

30 Jun 2023 bởi

Treatment with pembrolizumab (pembro) in combination with gemcitabine and cisplatin (gem/cis) results in a statistically significant, clinically meaningful improvement in overall survival (OS) when compared with placebo plus gem/cis in patients with previously untreated metastatic or unresectable biliary tract cancer (BTC), results of the KEYNOTE-966 study have shown.

Pembrolizumab plus gemcitabine/cisplatin improves survival in metastatic biliary tract cancer

30 Jun 2023

Long-term data support teduglutide safety for SBS-IF

30 Jun 2023 bởi

In a pooled analysis of two long-term paediatric extension trials evaluating short bowel syndrome-associated intestinal failure (SBS-IF), the glucagon-like peptide-2 analogue teduglutide (TED) demonstrated a safety profile that aligned with previous data.

Long-term data support teduglutide safety for SBS-IF

30 Jun 2023

Does vitamin D therapy improve survival in patients with CKD?

30 Jun 2023

For patients with chronic kidney disease (CKD), vitamin D therapy does little to reduce the risk of all-cause death, according to a study.

Does vitamin D therapy improve survival in patients with CKD?

30 Jun 2023

$Faecal transplant helps teens with refractory IBS$

Faecal transplant helps teens with refractory IBS

29 Jun 2023 bởi

For adolescents with treatment-refractory irritable bowel syndrome (IBS), faecal microbiota transplantation (FMT) is safe and beneficial, easing abdominal pain and improving health-related quality of life, according to a study presented at ESPGHAN 2023.

Faecal transplant helps teens with refractory IBS

29 Jun 2023

Pegargiminase plus chemo improves survival in nonepithelioid pleural mesothelioma

29 Jun 2023 bởi

Chemotherapy with pemetrexed and cisplatin with ADI-PEG20 (pegargiminase), an arginine-depleting agent, results in better survival and demonstrates a favourable safety profile in patients with nonepithelioid pleural mesothelioma (PM), according to a study presented at AACR 2023.

Pegargiminase plus chemo improves survival in nonepithelioid pleural mesothelioma

29 Jun 2023

PPI use ups mortality risk in ICU patients

29 Jun 2023

Use of proton pump inhibitors (PPIs) for the prevention of stress ulceration appears to elevate the risk of mortality in patients admitted to the intensive care unit (ICU), reveals a study.

PPI use ups mortality risk in ICU patients

29 Jun 2023

DOACs as good as LMWH for recurrent VTE prevention in cancer patients

29 Jun 2023

For patients with cancer who have recurrent venous thromboembolism (VTE), direct oral anticoagulants (DOACs) compare favourably with low-molecular-weight heparin (LMWH) in terms of recurrence prevention, according to a study.

DOACs as good as LMWH for recurrent VTE prevention in cancer patients

29 Jun 2023

Real-world data back CV safety of JAK inhibitors

28 Jun 2023 bởi

Two real-world studies presented at EULAR 2023 reflected the cardiovascular (CV) safety of Janus kinase inhibitors (JAKi*) in patients with rheumatoid arthritis (RA).

Real-world data back CV safety of JAK inhibitors

28 Jun 2023

Bempedoic acid beneficial for prevention of cardiac events in high-risk patients

28 Jun 2023

The use of bempedoic acid in primary prevention appears to lower the incidence of major cardiovascular events for high-risk patients, as shown in the subgroup analysis of the CLEAR Outcomes* trial.

Bempedoic acid beneficial for prevention of cardiac events in high-risk patients

28 Jun 2023

$Uricase-based combo therapy promising for refractory gout$

Uricase-based combo therapy promising for refractory gout

28 Jun 2023 bởi

Half of gout patients receiving novel uricase analogue infusions, along with a proprietary rapamycin formulation, got their serum urate controlled in two phase III studies presented at EULAR 2023.

Uricase-based combo therapy promising for refractory gout

28 Jun 2023

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Pembrolizumab plus gemcitabine/cisplatin improves survival in metastatic biliary tract cancer

Pembrolizumab plus gemcitabine/cisplatin improves survival in metastatic biliary tract cancer

Long-term data support teduglutide safety for SBS-IF

Long-term data support teduglutide safety for SBS-IF

Does vitamin D therapy improve survival in patients with CKD?

Does vitamin D therapy improve survival in patients with CKD?

Faecal transplant helps teens with refractory IBS

Faecal transplant helps teens with refractory IBS

Pegargiminase plus chemo improves survival in nonepithelioid pleural mesothelioma

Pegargiminase plus chemo improves survival in nonepithelioid pleural mesothelioma

PPI use ups mortality risk in ICU patients

PPI use ups mortality risk in ICU patients

DOACs as good as LMWH for recurrent VTE prevention in cancer patients

DOACs as good as LMWH for recurrent VTE prevention in cancer patients

Real-world data back CV safety of JAK inhibitors

Real-world data back CV safety of JAK inhibitors

Bempedoic acid beneficial for prevention of cardiac events in high-risk patients

Bempedoic acid beneficial for prevention of cardiac events in high-risk patients

Uricase-based combo therapy promising for refractory gout

Uricase-based combo therapy promising for refractory gout