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Long-acting CAB+RPV injections feasible in teens with HIV

06 Aug 2024 bởi

Virally suppressed adolescents living with HIV-1 who switched from daily oral to long-acting (LA) injectable cabotegravir (CAB) plus rilpivirine (RPV) every 8 weeks show an acceptable safety profile, with pharmacokinetics similar to adults, according to the week-48 results of the IMPAACT 2017 study.

Long-acting CAB+RPV injections feasible in teens with HIV

06 Aug 2024

Female AYA cancer survivors: Are they at risk for adverse obstetric outcomes?

06 Aug 2024 bởi

Female adolescent and young adult (AYA) survivors of certain types of cancer appear to be at risk of birth rate deficits and obstetric complications, suggests a retrospective study from the UK.

Female AYA cancer survivors: Are they at risk for adverse obstetric outcomes?

06 Aug 2024

Statin overuse in acute cerebral ischaemia linked to thousands of AEs per year

06 Aug 2024

More than one-fifth of patients with acute cerebral ischaemia (ACI) appear to be receiving statins unnecessarily, which has the potential to cause higher than 5,600 adverse events (AEs) each year, including diabetes, myopathy, and eye disease, according to the results of a meta-analysis.

Statin overuse in acute cerebral ischaemia linked to thousands of AEs per year

06 Aug 2024

Original New Drug Application Approvals by US FDA (16-31 July 2024)

06 Aug 2024

New drug applications approved by US FDA as of 16-31 July 2024 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-31 July 2024)

06 Aug 2024

Less risk, same benefit with relugolix combination vs monotherapy for endometriosis-related pain

05 Aug 2024 bởi

In the treatment of women with endometriosis-associated pain, relugolix combination has a risk-benefit profile that is more favourable than that of monotherapy, due to the latter contributing to increased vasomotor symptoms and substantial bone mineral density (BMD) loss, as shown in a study.

Less risk, same benefit with relugolix combination vs monotherapy for endometriosis-related pain

05 Aug 2024

Giant cell arteritis diagnosis raises healthcare costs

05 Aug 2024

People diagnosed with giant cell arteritis (GCA) tend to have higher healthcare expenses during all three phases of care, according to a study conducted in Ontario, Canada.

Giant cell arteritis diagnosis raises healthcare costs

05 Aug 2024

How viable is a self-administered injection in adults with HIV?

05 Aug 2024 bởi

A substudy of the phase III FLAIR study has found comparable efficacy and pharmacokinetics for cabotegravir (CAB) plus rilpivirine (RPV) via subcutaneous (SC) administration relative to those via intramuscular (IM) gluteal injections among virally suppressed individuals living with HIV-1.

How viable is a self-administered injection in adults with HIV?

05 Aug 2024

Peri-infarct ischaemia predicts adverse cardiac events

05 Aug 2024

Peri-infarct ischaemia, detected by stress cardiac magnetic imaging, is significantly associated with adverse cardiovascular events, a study has shown.

Peri-infarct ischaemia predicts adverse cardiac events

05 Aug 2024

KEYNOTE-585 final analysis support perioperative pembrolizumab-chemo for G/GEJ cancer

05 Aug 2024 bởi

Perioperative pembrolizumab plus chemotherapy confers survival benefit in individuals with locally advanced gastric and gastroesophageal junction (G/GEJ) cancer in the final analysis of the phase III KEYNOTE-585 trial.

KEYNOTE-585 final analysis support perioperative pembrolizumab-chemo for G/GEJ cancer

05 Aug 2024

Low-dose aspirin exerts no effect on progression of age-related hearing loss

05 Aug 2024

Daily intake of 100-mg aspirin over 3 years does not appear to limit the progression of age-related hearing loss, according to a secondary analysis of the ASPREE study.

Low-dose aspirin exerts no effect on progression of age-related hearing loss

05 Aug 2024

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Long-acting CAB+RPV injections feasible in teens with HIV

Long-acting CAB+RPV injections feasible in teens with HIV

Female AYA cancer survivors: Are they at risk for adverse obstetric outcomes?

Female AYA cancer survivors: Are they at risk for adverse obstetric outcomes?

Statin overuse in acute cerebral ischaemia linked to thousands of AEs per year

Statin overuse in acute cerebral ischaemia linked to thousands of AEs per year

Original New Drug Application Approvals by US FDA (16-31 July 2024)

Original New Drug Application Approvals by US FDA (16-31 July 2024)

Less risk, same benefit with relugolix combination vs monotherapy for endometriosis-related pain

Less risk, same benefit with relugolix combination vs monotherapy for endometriosis-related pain

Giant cell arteritis diagnosis raises healthcare costs

Giant cell arteritis diagnosis raises healthcare costs

How viable is a self-administered injection in adults with HIV?

How viable is a self-administered injection in adults with HIV?

Peri-infarct ischaemia predicts adverse cardiac events

Peri-infarct ischaemia predicts adverse cardiac events

KEYNOTE-585 final analysis support perioperative pembrolizumab-chemo for G/GEJ cancer

KEYNOTE-585 final analysis support perioperative pembrolizumab-chemo for G/GEJ cancer

Low-dose aspirin exerts no effect on progression of age-related hearing loss

Low-dose aspirin exerts no effect on progression of age-related hearing loss