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Treatment with mirikizumab results in significant improvements in clinical, endoscopic, and histologic outcomes during induction and maintenance phases in patients with Crohn’s disease (CD) or ulcerative colitis (UC), according to an updated meta-analysis of randomized controlled trials (RCTs).

Mirikizumab improves IBD outcomes during induction, maintenance periods

Vedolizumab vs ustekinumab: Which holds greater advantage for patients with CD?

Treatment with either vedolizumab or ustekinumab delivers significant and meaningful benefits to patients with Crohn’s disease (CD), but each has its distinct therapeutic profile with complementary advantages, reports a real-world study presented at CCC 2026.

Vedolizumab vs ustekinumab: Which holds greater advantage for patients with CD?

Drinking water salinity may affect BP levels

A systematic review and meta-analysis show an association between elevated salinity in drinking water and higher systolic blood pressure (SBP) and diastolic BP (DBP) levels, particularly among individuals residing in coastal areas.

Drinking water salinity may affect BP levels

Peppermint oil, sweets of little benefit in paediatric IBS and functional abdominal pain

Peppermint oil or peppermint sweets appear to do little in terms of relieving pain in children with irritable bowel syndrome (IBS) or functional abdominal pain–not otherwise specified, as shown in a study.

Peppermint oil, sweets of little benefit in paediatric IBS and functional abdominal pain

Intra-arterial alteplase after successful EVT yields excellent functional outcome in adults

The use of intra-arterial (IA) alteplase following a successful endovascular thrombectomy (EVT) improves 90-day functional outcome in patients with large-vessel occlusion (LVO) acute ischaemic stroke compared with EVT-alone, according to the CHOICE 2* trial presented at ISC 2026.

Intra-arterial alteplase after successful EVT yields excellent functional outcome in adults

Single intranasal dose of live-attenuated vaccine confers broad protection against coronaviruses, including SARS-CoV-2

A single intranasal dose of a live-attenuated broad-spectrum coronavirus vaccine developed at the University of Hong Kong (HKU) elicits broad, potent and long-lasting immunity against diverse SARS-CoV-2 variants of concern (VoCs) and more divergent SARS-CoV-1 and hCoV-OC43 that translates into complete protection in animal models, including prevention of viral transmission to unvaccinated contacts.

Single intranasal dose of live-attenuated vaccine confers broad protection against coronaviruses, including SARS-CoV-2

13 Feb 2026

Shortened romosozumab course proves beneficial in postmenopausal osteoporosis

12 Feb 2026 bởi

Three months of romosozumab followed by 9 months of denosumab works just as well as 12 months of romosozumab for increasing bone mass in postmenopausal women at high risk of fracture, as shown in an open-label, noninferiority trial.

Shortened romosozumab course proves beneficial in postmenopausal osteoporosis

Sleep efficiency tied to 24-h BPV, but not duration, quality

Adults with elevated blood pressure (BP) who have better sleep efficiency tend to show lower short-term BP variability (BPV), reveals a study. However, longer sleep duration and perceived sleep quality appear to have no significant association with BPV.

Sleep efficiency tied to 24-h BPV, but not duration, quality

A recent study in Japan has observed a reduction in psychological stress and healthier mental health states among adolescents living in Tokyo during the COVID-19 pandemic.

Mental health of high school students improved during pandemic: study

12 Feb 2026 bởi

Mental health of high school students improved during pandemic: study

12 Feb 2026

Early PoPH linked to mortality in patients with cirrhosis

The use of the 2022 ESC/ERC definitions of pulmonary arterial hypertension (PAH) has led to the identification of cirrhosis patients with early-stage portopulmonary hypertension (PoPH), who are at greater risk of death, reports a study.

Early PoPH linked to mortality in patients with cirrhosis