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Tinengotinib shows promising activity against cholangiocarcinoma

16 Dec 2025

In patients with cholangiocarcinoma with FGFR2 fusions that progressed following FGFR inhibitor therapy, tinengotinib has demonstrated potential antitumour activity in a phase II study.

Tinengotinib shows promising activity against cholangiocarcinoma

16 Dec 2025

Oral PCSK9 inhibitor lowers LDL-C by up to 60 percent

16 Dec 2025 bởi

The oral PCSK9 inhibitor enlicitide lowers LDL-cholesterol (LDL-C) levels and other atherogenic lipids in high-risk patients with hypercholesterolaemia, as shown in the CORALreef Lipids study presented at AHA 2025.

Oral PCSK9 inhibitor lowers LDL-C by up to 60 percent

16 Dec 2025

Deaths from C. difficile higher in women, White patients

16 Dec 2025 bởi

Despite advances in infection control and antimicrobial stewardship, mortality from Clostridioides difficile (C. difficile) enterocolitis continues to disproportionately affect certain populations in the US, according to an analysis of the CDC WONDER database presented at IDWeek 2025.

Deaths from C. difficile higher in women, White patients

16 Dec 2025

HFrEF outcomes due to Chagas disease no better with sacubitril/valsartan vs enalapril

15 Dec 2025

In the treatment of patients with heart failure with reduced ejection fraction (HFrEF) secondary to Chagas disease, the use of sacubitril/valsartan does not appear to lead to improvements in clinical outcomes compared with enalapril, according to a study.

HFrEF outcomes due to Chagas disease no better with sacubitril/valsartan vs enalapril

15 Dec 2025

Laughing gas touted as rapid-acting antidepressant in meta-analysis

15 Dec 2025 bởi

Administration of nitrous oxide (N2O) appears to alleviate depressive symptoms as quickly as 2 h, according to a meta-analysis.

Laughing gas touted as rapid-acting antidepressant in meta-analysis

15 Dec 2025

Sedentary behaviour tied to arterial stiffness in older adults

15 Dec 2025

A sedentary behaviour appears to contribute to increased arterial stiffness among older adults, suggests a recent study.

Sedentary behaviour tied to arterial stiffness in older adults

15 Dec 2025

Mindfulness-based interventions may ease burnout among HCPs

15 Dec 2025

Mindfulness-based interventions are helpful in reducing burnout among nurses and midwives, as well as among a mixture of healthcare professionals (HCPs), but professional coaching appears more beneficial among physicians, especially when done for more than 4 weeks, suggests a study.

Mindfulness-based interventions may ease burnout among HCPs

15 Dec 2025

Tai chi vs CBT: Which is better for treating insomnia in adults?

15 Dec 2025 bởi

A recent study has shown that tai chi is less effective than cognitive behavioural therapy for insomnia (CBT-I) at 3 months, but it is no longer inferior to CBT-I at month 15.

Tai chi vs CBT: Which is better for treating insomnia in adults?

15 Dec 2025

Arterial stiffness linked to small-, large-fiber neuropathy

15 Dec 2025 bởi

A recent study has shown the association of greater arterial stiffening with both ocular (small) and peripheral (large) fiber neuropathies.

Arterial stiffness linked to small-, large-fiber neuropathy

15 Dec 2025

Systemic vascular resistance higher in people with family history of hypertension

15 Dec 2025

Individuals with a family history of hypertension show increased central and peripheral blood pressure (BP) potentially due to higher systemic vascular resistance (SVR), according to a study. On the other hand, large artery stiffness is not elevated.

Systemic vascular resistance higher in people with family history of hypertension

15 Dec 2025

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Tinengotinib shows promising activity against cholangiocarcinoma

Tinengotinib shows promising activity against cholangiocarcinoma

Oral PCSK9 inhibitor lowers LDL-C by up to 60 percent

Oral PCSK9 inhibitor lowers LDL-C by up to 60 percent

Deaths from C. difficile higher in women, White patients

Deaths from C. difficile higher in women, White patients

HFrEF outcomes due to Chagas disease no better with sacubitril/valsartan vs enalapril

HFrEF outcomes due to Chagas disease no better with sacubitril/valsartan vs enalapril

Laughing gas touted as rapid-acting antidepressant in meta-analysis

Laughing gas touted as rapid-acting antidepressant in meta-analysis

Sedentary behaviour tied to arterial stiffness in older adults

Sedentary behaviour tied to arterial stiffness in older adults

Mindfulness-based interventions may ease burnout among HCPs

Mindfulness-based interventions may ease burnout among HCPs

Tai chi vs CBT: Which is better for treating insomnia in adults?

Tai chi vs CBT: Which is better for treating insomnia in adults?

Arterial stiffness linked to small-, large-fiber neuropathy

Arterial stiffness linked to small-, large-fiber neuropathy

Systemic vascular resistance higher in people with family history of hypertension

Systemic vascular resistance higher in people with family history of hypertension