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The addition of eldecalcitol therapy to risedronate results in increased lumbar spine (LS) bone mineral density (BMD) in osteopenic to osteoporotic postmenopausal women with breast cancer who are receiving an aromatase inhibitor (AI), according to a study.

Eldecalcitol add-on therapy prevents bone loss in postmenopausal breast cancer patients

Can time restricted eating plus exercise improve glycaemic control during pregnancy?

Time restricted eating combined with exercise training started before and continued throughout pregnancy does not provide any significant impact on glycaemic control during late pregnancy, reveals a recent study.

Can time restricted eating plus exercise improve glycaemic control during pregnancy?

Is it safe to use high-dose PTZ in critically ill patients with obesity?

High piperacillin-tazobactam (PTZ) dosing does not lead to increased acute nephrotoxicity, thrombocytopenia, 14-day all-cause mortality, or intensive care unit (ICU) length of stay (LOS), suggests a recent study.

Is it safe to use high-dose PTZ in critically ill patients with obesity?

Bariatric surgery more effective, affordable than GLP-1RAs for severe obesity

For individuals with class II and III obesity, metabolic bariatric surgery appears to result in durable weight loss at lower ongoing costs when compared with glucagon-like peptide-1 receptor agonists (GLP-1RAs), according to a study.

Bariatric surgery more effective, affordable than GLP-1RAs for severe obesity

Energy-reduced MedDiet plus physical activity prevents T2D in persons with obesity

An intensive intervention with energy-reduced Mediterranean diet (MedDiet) combined with physical activity demonstrates greater efficacy than an ad libitum MedDiet only in lowering the incidence of diabetes in persons with overweight or obesity and metabolic syndrome, according to a study.

Energy-reduced MedDiet plus physical activity prevents T2D in persons with obesity

Pomegranate supplementation mitigates several cardiometabolic risk factors

Pomegranate supplementation helps improve certain risk factors for cardiometabolic syndrome, including body weight, BMI, blood pressure, fasting blood glucose, total cholesterol, and high-density lipoprotein (HDL), according to a systematic review and meta-analysis.

Pomegranate supplementation mitigates several cardiometabolic risk factors

Original New Drug Application Approvals by US FDA (16-31 August 2025)

New drug applications approved by US FDA as of 16-31 August 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-31 August 2025)