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EPVS burden a potential marker of CSVD, AD-related pathology

17 Dec 2025 bởi

A study from Singapore reports the potential of enlarged perivascular space (EPVS) burden as a marker of cerebral small vessel disease (CSVD) and Alzheimer’s disease (AD)-related blood-based biomarker (BBM) pathology.

EPVS burden a potential marker of CSVD, AD-related pathology

17 Dec 2025

Arterial stiffness linked to small-, large-fiber neuropathy

15 Dec 2025 bởi

A recent study has shown the association of greater arterial stiffening with both ocular (small) and peripheral (large) fiber neuropathies.

Arterial stiffness linked to small-, large-fiber neuropathy

15 Dec 2025

Sleep apnoea may pose increased Parkinson’s disease risk

11 Dec 2025 bởi

People with obstructive sleep apnoea seem predisposed to later development of Parkinson’s disease, but this risk can be mitigated by early treatment with continuous positive airway pressure, as reported in a study.

Sleep apnoea may pose increased Parkinson’s disease risk

11 Dec 2025

Epilepsy risk elevated in children with congenital Zika syndrome

10 Dec 2025 bởi

New research suggests that in-utero exposure to Zika virus (ZIKV) alone does not increase the risk of epilepsy in early childhood, and the risk increase is limited to children who develop congenital Zika syndrome.

Epilepsy risk elevated in children with congenital Zika syndrome

10 Dec 2025

Plasma p-tau217 detects Alzheimer's disease in preclinical stage

09 Dec 2025 bởi

Plasma phosphorylated tau 217 (p-tau217) can identify pathological changes characteristic of Alzheimer’s disease (AD) in older adults without cognitive impairment, according to a meta-analysis.

Plasma p-tau217 detects Alzheimer's disease in preclinical stage

09 Dec 2025

Perimenopausal hormonal imbalances drive Alzheimer’s risk, plasma E2:P4 ratio a potential biomarker

09 Dec 2025 bởi

Researchers from the School of Life Sciences and the Gerald Choa Neuroscience Institute at the Chinese University of Hong Kong (CUHK) have found that estradiol (E2) to progesterone (P4) (E2:P4) imbalance during perimenopause likely increases the risk of Alzheimer’s disease (AD) and AD-related dementia in women via oestrogen-related receptor alpha (ERRα) dysfunction.

Perimenopausal hormonal imbalances drive Alzheimer’s risk, plasma E2:P4 ratio a potential biomarker

09 Dec 2025

Getting physically active in midlife, late life lowers dementia risk

08 Dec 2025 bởi

Higher levels of physical activity help fight dementia, especially for middle-aged and older adults, according to a study.

Getting physically active in midlife, late life lowers dementia risk

08 Dec 2025

Premotor phase biomarkers may enable early PD diagnosis

08 Dec 2025

Premotor phase biomarkers can be as accurate as motor phase biomarkers in diagnosing Parkinson’s disease (PD), offering an earlier diagnosis compared with clinical methods, suggests a study.

Premotor phase biomarkers may enable early PD diagnosis

08 Dec 2025

PPI use hurts survival outcomes in glioblastoma

08 Dec 2025

In patients with newly diagnosed glioblastoma, the use proton pump inhibitors (PPI) may be detrimental to survival, according to a meta-analysis.

PPI use hurts survival outcomes in glioblastoma

08 Dec 2025

Mediterranean diet helps reduce migraine attacks

05 Dec 2025

Mediterranean-style eating, omega-3 supplementation, and selective trials of ketogenic or elimination approaches may help in the management of migraine, suggests a study.

Mediterranean diet helps reduce migraine attacks

05 Dec 2025

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EPVS burden a potential marker of CSVD, AD-related pathology

EPVS burden a potential marker of CSVD, AD-related pathology

Arterial stiffness linked to small-, large-fiber neuropathy

Arterial stiffness linked to small-, large-fiber neuropathy

Sleep apnoea may pose increased Parkinson’s disease risk

Sleep apnoea may pose increased Parkinson’s disease risk

Epilepsy risk elevated in children with congenital Zika syndrome

Epilepsy risk elevated in children with congenital Zika syndrome

Plasma p-tau217 detects Alzheimer's disease in preclinical stage

Plasma p-tau217 detects Alzheimer's disease in preclinical stage

Perimenopausal hormonal imbalances drive Alzheimer’s risk, plasma E2:P4 ratio a potential biomarker

Perimenopausal hormonal imbalances drive Alzheimer’s risk, plasma E2:P4 ratio a potential biomarker

Getting physically active in midlife, late life lowers dementia risk

Getting physically active in midlife, late life lowers dementia risk

Premotor phase biomarkers may enable early PD diagnosis

Premotor phase biomarkers may enable early PD diagnosis

PPI use hurts survival outcomes in glioblastoma

PPI use hurts survival outcomes in glioblastoma

Mediterranean diet helps reduce migraine attacks

Mediterranean diet helps reduce migraine attacks