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Cutting first-day dexamethasone dose not recommended for breast cancer patients on anthracycline
In breast cancer patients treated with anthracycline-containing regimens, reducing the first-day dose of dexamethasone does not yield significant gastrointestinal benefit and is not recommended for nausea management, a recent study has found.

Low-dose aspirin does not stave off dementia
A daily 100 mg dose of aspirin for 7 years did not reduce the risk of dementia in individuals with diabetes and no history of cardiovascular disease (CVD), according to results of the ASCEND* study presented at AHA 2021.

Guselkumab safe, well tolerated in patients with psoriatic arthritis
Treatment with the monoclonal antibody targeting interleukin [IL]-23p19 guselkumab 100 mg, given either every 4 (Q4W) or 8 weeks (Q8W), is well tolerated in patients with psoriatic arthritis (PsA), with no new safety concerns through 1 year, according to pooled results of the DISCOVER-1 and DISCOVER-2 phase III trials.

Short-course, high-dose gatifloxacin gets a pass in multidrug-resistant TB with caveat
A short-term treatment regimen based on high-dose gatifloxacin appears to be effective against multidrug- or rifampicin-resistant tuberculosis (TB) but at the cost of increased severe adverse drug reactions, as shown in a study.




