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Detecting Alzheimer’s disease biomarkers: Timing matters

02 May 2024 bởi

A 20-year nested case–control study in China has shown sequential and temporal changes in biomarkers 6–18 years before diagnosis of Alzheimer’s disease (AD). Accelerated changes in cerebrospinal fluid (CSF) biomarkers were found after the onset of cognitive impairment, followed by plateaus at AD diagnosis.

Detecting Alzheimer’s disease biomarkers: Timing matters

02 May 2024

Medroxyprogesterone acetate a viable option for preventing ovulation during IVF

02 May 2024

In women undergoing autologous in vitro fertilization (IVF) for fertility treatment, ovulatory suppression with medroxyprogesterone acetate proves effective, with cycle and reproductive outcomes similar to that with gonadotropin-releasing hormone (GnRH) antagonist and the advantage of being cheaper, according to a study.

Medroxyprogesterone acetate a viable option for preventing ovulation during IVF

02 May 2024

Oral lasofoxifene helps improve genitourinary syndrome of menopause

01 May 2024

Oral lasofoxifene at either 0.25 or 0.5 mg daily confers benefits on genitourinary syndrome of menopause, with pooled data from two phase III trials showing significant improvements in vaginal signs or symptoms while having a favourable safety profile.

Oral lasofoxifene helps improve genitourinary syndrome of menopause

01 May 2024

Conformable, ‘single-shot’ pulsed field ablation catheter scores high for pulmonary vein isolation

01 May 2024 bởi

A novel “single-shot,” large-lattice pulsed field ablation (PFA) catheter that conforms to diverse left atrial and pulmonary vein anatomies is safe and efficacious for isolating pulmonary veins in patients with paroxysmal atrial fibrillation (AF), as shown in a first-in-human trial.

Conformable, ‘single-shot’ pulsed field ablation catheter scores high for pulmonary vein isolation

01 May 2024

Thrombectomy tied to better functional outcomes in large ischaemic stroke patients

01 May 2024 bởi

Endovascular thrombectomy (EVT) in addition to medical care results in significantly improved functional outcomes at 1 year in acute ischaemic stroke patients with a large core infarct compared with medical care alone, as shown in the SELECT2 study. This benefit persists across ischaemic core strata on imaging.

Thrombectomy tied to better functional outcomes in large ischaemic stroke patients

01 May 2024

Plant-based diet may mitigate risk of death in CKD

01 May 2024

Among people with chronic kidney disease (CKD), those who adhere to an overall plant-based diet and a healthy plant-based diet are at lower risk of all-cause mortality, whereas those who follow an unhealthy plant-based diet are at increased risk of CKD progression and all-cause mortality, according to a study.

Plant-based diet may mitigate risk of death in CKD

01 May 2024

Debunking the myths about DPP-4 inhibitors

01 May 2024

Navigating the evolving landscape of diabetes management requires precise knowledge. In this exploration into the world of DPP-4 inhibitors (DPP4is), we aim to debunk prevalent myths and provide nuanced insights.

Debunking the myths about DPP-4 inhibitors

01 May 2024

Improved cervical screening uptake among local South Asian women following CUHK training

01 May 2024 bởi

Expansion of a territory-wide cervical screening programme to train a group of local South Asian women has enabled education regarding cervical cancer and screening services among their peers, and considerably improved screening uptake.

Improved cervical screening uptake among local South Asian women following CUHK training

01 May 2024

Antenatal corticosteroid exposure poses no major threat to infant neurodevelopment

30 Apr 2024

Children who were exposed antenatally to betamethasone as opposed to placebo are not necessarily at a disadvantage in terms of neurodevelopment outcomes, as shown in a follow-up to the Antenatal Late Preterm Steroids (ALPS) trial.

Antenatal corticosteroid exposure poses no major threat to infant neurodevelopment

30 Apr 2024

Anticoagulation of little benefit to patients with device-detected AF, multiple comorbidities

30 Apr 2024 bởi

Giving oral anticoagulants to patients with device-detected atrial fibrillation (AF) and multiple comorbidities does not necessarily help lower the rate of cardiovascular events, according to a subgroup analysis of the NOAH-AFNET 6 trial.

Anticoagulation of little benefit to patients with device-detected AF, multiple comorbidities

30 Apr 2024

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Detecting Alzheimer’s disease biomarkers: Timing matters

Detecting Alzheimer’s disease biomarkers: Timing matters

Medroxyprogesterone acetate a viable option for preventing ovulation during IVF

Medroxyprogesterone acetate a viable option for preventing ovulation during IVF

Oral lasofoxifene helps improve genitourinary syndrome of menopause

Oral lasofoxifene helps improve genitourinary syndrome of menopause

Conformable, ‘single-shot’ pulsed field ablation catheter scores high for pulmonary vein isolation

Conformable, ‘single-shot’ pulsed field ablation catheter scores high for pulmonary vein isolation

Thrombectomy tied to better functional outcomes in large ischaemic stroke patients

Thrombectomy tied to better functional outcomes in large ischaemic stroke patients

Plant-based diet may mitigate risk of death in CKD

Plant-based diet may mitigate risk of death in CKD

Debunking the myths about DPP-4 inhibitors

Debunking the myths about DPP-4 inhibitors

Improved cervical screening uptake among local South Asian women following CUHK training

Improved cervical screening uptake among local South Asian women following CUHK training

Antenatal corticosteroid exposure poses no major threat to infant neurodevelopment

Antenatal corticosteroid exposure poses no major threat to infant neurodevelopment

Anticoagulation of little benefit to patients with device-detected AF, multiple comorbidities

Anticoagulation of little benefit to patients with device-detected AF, multiple comorbidities