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Ultraprocessed food intake a culprit in reduced handgrip strength in Asians

24 Jul 2025 bởi

New research from Singapore shows that individuals with a higher intake of ultraprocessed foods (UPF) during their midlife years are likely to have lower handgrip strength in later life.

Ultraprocessed food intake a culprit in reduced handgrip strength in Asians

24 Jul 2025

BP status mediates link between kidney, vascular health biomarkers in young adults

24 Jul 2025

Mechanisms associated with early nephron-specific kidney injury biomarkers in young adults vary according to the blood pressure (BP) status, reports a study.

BP status mediates link between kidney, vascular health biomarkers in young adults

24 Jul 2025

How do parents perceive physical activity in children with cancer?

24 Jul 2025 bởi

The role of the family is critical to the encouragement of physical activity (PA) among childhood cancer survivors (CCS), according to a Singapore study. Apart from individuals and families, the community and society can also influence participation in PA.

How do parents perceive physical activity in children with cancer?

24 Jul 2025

First-line NUC-1031/cisplatin trial for advanced BTC cut short due to futility

24 Jul 2025

A recent phase III trial of NUC-1031/cisplatin has been terminated early due to ineffectiveness as first-line treatment for advanced biliary tract cancer (BTC).

First-line NUC-1031/cisplatin trial for advanced BTC cut short due to futility

24 Jul 2025

Deutetrabenazine for tardive dyskinesia yields favourable patient-reported outcomes

24 Jul 2025 bởi

Individuals with tardive dyskinesia (TD) report favourable outcomes with the VMAT2 inhibitor deutetrabenazine in an age subgroup analysis.

Deutetrabenazine for tardive dyskinesia yields favourable patient-reported outcomes

24 Jul 2025

Sarilumab helps improve patient-reported outcomes in relapsing polymyalgia rheumatica

24 Jul 2025

In the treatment of patients with relapsing polymyalgia rheumatica who have had an inadequate response to corticosteroids or who cannot tolerate corticosteroid taper, the use of sarilumab appears to produce clinically important improvements in health-related quality of life and patient-reported outcomes, according to the results of a phase III study.

Sarilumab helps improve patient-reported outcomes in relapsing polymyalgia rheumatica

24 Jul 2025

TOPAZ-1: Greater numeric improvement in OS among biliary tract cancer patients with immune-mediated AEs

24 Jul 2025 bởi

A post-hoc analysis of the phase III TOPAZ-1 study of durvalumab plus gemcitabine and cisplatin (GemCis) in advanced biliary tract cancer (aBTC) has found that while durvalumab demonstrated an overall survival (OS) benefit vs placebo irrespective of immune-mediated adverse events (imAEs), the improvement in OS was numerically greater among patients who experienced imAEs.

TOPAZ-1: Greater numeric improvement in OS among biliary tract cancer patients with immune-mediated AEs

24 Jul 2025

KEYNOTE-826: Pembrolizumab + chemo +/- bevacizumab improves PFS and OS in East Asians with cervical cancer

24 Jul 2025 bởi

The addition of pembrolizumab to chemotherapy with or without bevacizumab significantly improves progression-free survival (PFS) and overall survival (OS) in East Asian patients with persistent, recurrent or metastatic cervical cancer, according to an exploratory analysis of the final results from the phase III KEYNOTE-826 trial.

KEYNOTE-826: Pembrolizumab + chemo +/- bevacizumab improves PFS and OS in East Asians with cervical cancer

24 Jul 2025

Olorofim shows promise in invasive fungal disease

23 Jul 2025

In patients with invasive fungal disease (IFD) who have few or no treatment options, olorofim demonstrates efficacy and good tolerability, according to the results of a single-arm, open-label phase IIb study.

Olorofim shows promise in invasive fungal disease

23 Jul 2025

COVID-19 booster shots confer protection against severe disease in cancer patients

23 Jul 2025 bởi

Patients with cancer who have received COVID-19 booster vaccinations are better protected against severe disease, according to real-world data from four healthcare systems in the US.

COVID-19 booster shots confer protection against severe disease in cancer patients

23 Jul 2025

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Ultraprocessed food intake a culprit in reduced handgrip strength in Asians

Ultraprocessed food intake a culprit in reduced handgrip strength in Asians

BP status mediates link between kidney, vascular health biomarkers in young adults

BP status mediates link between kidney, vascular health biomarkers in young adults

How do parents perceive physical activity in children with cancer?

How do parents perceive physical activity in children with cancer?

First-line NUC-1031/cisplatin trial for advanced BTC cut short due to futility

First-line NUC-1031/cisplatin trial for advanced BTC cut short due to futility

Deutetrabenazine for tardive dyskinesia yields favourable patient-reported outcomes

Deutetrabenazine for tardive dyskinesia yields favourable patient-reported outcomes

Sarilumab helps improve patient-reported outcomes in relapsing polymyalgia rheumatica

Sarilumab helps improve patient-reported outcomes in relapsing polymyalgia rheumatica

TOPAZ-1: Greater numeric improvement in OS among biliary tract cancer patients with immune-mediated AEs

TOPAZ-1: Greater numeric improvement in OS among biliary tract cancer patients with immune-mediated AEs

KEYNOTE-826: Pembrolizumab + chemo +/- bevacizumab improves PFS and OS in East Asians with cervical cancer

KEYNOTE-826: Pembrolizumab + chemo +/- bevacizumab improves PFS and OS in East Asians with cervical cancer

Olorofim shows promise in invasive fungal disease

Olorofim shows promise in invasive fungal disease

COVID-19 booster shots confer protection against severe disease in cancer patients

COVID-19 booster shots confer protection against severe disease in cancer patients