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Maintenance fuzuloparib prolongs survival in ovarian cancer

12 Apr 2024 bởi

Maintenance therapy with fuzuloparib results in significant improvements in progression-free survival (PFS) in patients newly diagnosed with advanced ovarian cancer, who showed response to first-line platinum-based chemotherapy (PBC), reports a study (FZOCUS-1) presented at SGO 2024.

Maintenance fuzuloparib prolongs survival in ovarian cancer

12 Apr 2024

Niraparib maintenance yields favourable OS trend in patients with ovarian cancer

12 Apr 2024 bởi

Maintenance treatment with niraparib, a potent, highly selective PARP* inhibitor, provides a favourable overall survival (OS) trend compared with placebo in Chinese patients with platinum-sensitive recurrent ovarian cancer (PSROC), regardless of germline BRCA (gBRCA) mutation status, according to the ﬁnal analysis of the NORA trial presented at SGO 2024.

Niraparib maintenance yields favourable OS trend in patients with ovarian cancer

12 Apr 2024

ATR inhibitor promise for advanced solid tumours dimmed by liver toxicity

10 Apr 2024

Gartisertib, an oral inhibitor of ataxia telangiectasia and Rad3-related protein (ATR), for patients with advanced solid tumours is well tolerated at lower doses, according to the results of a phase I study. However, unexpected liver toxicity prevents dose escalation and, in turn, limits the drug’s antitumour activity.

ATR inhibitor promise for advanced solid tumours dimmed by liver toxicity

10 Apr 2024

Growing incidence of HPV-positive oropharyngeal cancer in HK

09 Apr 2024 bởi

A retrospective study by the Chinese University of Hong Kong (CUHK) reports a growing incidence of oropharyngeal cancer, with an increasing proportion of human papillomavirus (HPV)–positive cases in Hong Kong in recent years.

Growing incidence of HPV-positive oropharyngeal cancer in HK

09 Apr 2024

Survival outcomes similar between minimally invasive interval debulking surgery and laparotomy

05 Apr 2024 bởi

A minimally invasive approach to interval debulking surgery appears to be just as effective as the use of an open technique for epithelial ovarian cancer, with no significant difference in overall survival (OS) when complete tumour resection is achieved, according to a study.

Survival outcomes similar between minimally invasive interval debulking surgery and laparotomy

05 Apr 2024

Noninvasive device targets precancerous cervical lesions with minimal risk

04 Apr 2024 bởi

A novel device that integrates hexaminolevulinate (HAL) hydrochloride (HCl) with photodynamic therapy for the treatment of cervical histologic high-grade squamous intraepithelial lesions (HSIL) has shown good results in the global phase III APRICITY study, with lasting efficacy and an acceptable safety profile.

Noninvasive device targets precancerous cervical lesions with minimal risk

04 Apr 2024

Endoscopic treatment shows therapeutic potential in severe duodenal polyposis

04 Apr 2024

In patients with severe duodenal polyposis, endoscopic treatment safely and effectively prevents cancer, offering a promising alternative to surgery, according to a study.

Endoscopic treatment shows therapeutic potential in severe duodenal polyposis

04 Apr 2024

H pylori eradication boosts survival outcomes for gastric cancer patients

03 Apr 2024

In gastric cancer patients with Helicobacter pylori infection, eradicating the infection leads to improved survival rates, as shown in a study.

H pylori eradication boosts survival outcomes for gastric cancer patients

03 Apr 2024

Pembrolizumab plus chemo ups survival in advanced endometrial cancer across MMR subgroups

02 Apr 2024 bởi

Adding pembrolizumab to standard chemotherapy resulted in a favourable overall survival (OS) benefit in patients with advanced or recurrent endometrial cancer compared with chemotherapy alone, regardless of mismatch repair (MMR) status, according to a key prespecified secondary analysis of the NRG-GY018 trial presented at the SGO 2024.

Pembrolizumab plus chemo ups survival in advanced endometrial cancer across MMR subgroups

02 Apr 2024

Unhealthy diet prevalent in childhood cancer survivors

01 Apr 2024

Many adult survivors of childhood cancer do not adhere to a healthful dietary pattern, particularly racial minorities and those with a lower socioeconomic status, reveals a study.

Unhealthy diet prevalent in childhood cancer survivors

01 Apr 2024

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Maintenance fuzuloparib prolongs survival in ovarian cancer

Maintenance fuzuloparib prolongs survival in ovarian cancer

Niraparib maintenance yields favourable OS trend in patients with ovarian cancer

Niraparib maintenance yields favourable OS trend in patients with ovarian cancer

ATR inhibitor promise for advanced solid tumours dimmed by liver toxicity

ATR inhibitor promise for advanced solid tumours dimmed by liver toxicity

Growing incidence of HPV-positive oropharyngeal cancer in HK

Growing incidence of HPV-positive oropharyngeal cancer in HK

Survival outcomes similar between minimally invasive interval debulking surgery and laparotomy

Survival outcomes similar between minimally invasive interval debulking surgery and laparotomy

Noninvasive device targets precancerous cervical lesions with minimal risk

Noninvasive device targets precancerous cervical lesions with minimal risk

Endoscopic treatment shows therapeutic potential in severe duodenal polyposis

Endoscopic treatment shows therapeutic potential in severe duodenal polyposis

H pylori eradication boosts survival outcomes for gastric cancer patients

H pylori eradication boosts survival outcomes for gastric cancer patients

Pembrolizumab plus chemo ups survival in advanced endometrial cancer across MMR subgroups

Pembrolizumab plus chemo ups survival in advanced endometrial cancer across MMR subgroups

Unhealthy diet prevalent in childhood cancer survivors

Unhealthy diet prevalent in childhood cancer survivors