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Prior herpes zoster vaccination mitigates long-term complications after infection

20 Nov 2025 bởi

For individuals who sustained herpes zoster infection, prior receipt of recombinant zoster vaccine appears to reduce the long-term risks of major adverse cardiovascular events, dementia, and death, according to a retrospective study.

Prior herpes zoster vaccination mitigates long-term complications after infection

20 Nov 2025

Radiotherapy vs imiquimod: Which is a better nonsurgical option for lentigo maligna?

20 Nov 2025

Radiotherapy and imiquimod are both efficacious and well-tolerated in patients with complex lentigo maligna who are not suitable for surgery, with no negative effects on health-related quality of life (HRQoL) at 24 months, reports a study.

Radiotherapy vs imiquimod: Which is a better nonsurgical option for lentigo maligna?

20 Nov 2025

Pivotal phase III trial shows Tx potential of oral carbapenem for cUTI or acute pyelonephritis

20 Nov 2025 bởi

Results from the phase III PIVOT-PO study demonstrate the potential of tebipenem pivoxil hydrobromide (TBP-PI) as an effective oral carbapenem antibiotic for the treatment of complicated urinary tract infections (cUTI).

Pivotal phase III trial shows Tx potential of oral carbapenem for cUTI or acute pyelonephritis

20 Nov 2025

For Asians with PCOS, ovarian reserve remains high even at advanced maternal age

19 Nov 2025 bởi

Asian women with polycystic ovary syndrome (PCOS) may have longer reproductive potential, with a high ovarian reserve that is maintained through older age and translates to increased success with assisted reproductive technology (ART) treatments, according to a retrospective study.

For Asians with PCOS, ovarian reserve remains high even at advanced maternal age

19 Nov 2025

JAK inhibitor exposure affects response to ritlecitinib for alopecia areata

19 Nov 2025

In patients with alopecia areata who received treatment with ritlecitinib, prior exposure to Janus kinase inhibitors is associated with reduced early response, reveals a study.

JAK inhibitor exposure affects response to ritlecitinib for alopecia areata

19 Nov 2025

Does antibiotic use prevent wound complications in episiotomy, second-degree tear?

19 Nov 2025 bởi

The use of prophylactic antibiotics shows no significant impact on overall wound complication but leads to a significant risk reduction in clinically relevant wound complications among women with episiotomies and second-degree tears, reports a study.

Does antibiotic use prevent wound complications in episiotomy, second-degree tear?

19 Nov 2025

Is high-dose IV push levetiracetam safe to administer?

19 Nov 2025

A recent study has provided further evidence on the safety and tolerability of rapid administration of undiluted levetiracetam, including 2,500- and 4,500-mg doses.

Is high-dose IV push levetiracetam safe to administer?

19 Nov 2025

High-dose flu vaccine extends benefit to adults aged 50–64 years

19 Nov 2025 bởi

A modified double-blind study shows the immunological superiority of high-dose (HD) over standard-dose (SD) inactivated influenza vaccine (IIV) in adults aged 50–64 years.

High-dose flu vaccine extends benefit to adults aged 50–64 years

19 Nov 2025

Enfortumab vedotin plus pembrolizumab confers survival benefit in MIBC

19 Nov 2025 bởi

Adding perioperative enfortumab vedotin and pembrolizumab (EV + pembro) to surgery with radical cystectomy plus standard pelvic lymph node dissection (RC + PLND) significantly improves event-free survival (EFS) and overall survival (OS) in patients with muscle-invasive bladder cancer (MIBC) who are ineligible for cisplatin-based therapy, based on the first interim analysis of the phase III KEYNOTE-905 study presented at ESMO 2025.

Enfortumab vedotin plus pembrolizumab confers survival benefit in MIBC

19 Nov 2025

Fixed-dose 4F-PCC safe, effective for FXal reversal in non-neurologic bleeds

18 Nov 2025

A fixed-dose four-factor prothrombin complex concentrate (4F-PCC) demonstrates both safety and efficacy for factor Xa inhibitor (FXal) reversal in patients with non-neurologic haemorrhage, according to a recent study.

Fixed-dose 4F-PCC safe, effective for FXal reversal in non-neurologic bleeds

18 Nov 2025

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Prior herpes zoster vaccination mitigates long-term complications after infection

Prior herpes zoster vaccination mitigates long-term complications after infection

Radiotherapy vs imiquimod: Which is a better nonsurgical option for lentigo maligna?

Radiotherapy vs imiquimod: Which is a better nonsurgical option for lentigo maligna?

Pivotal phase III trial shows Tx potential of oral carbapenem for cUTI or acute pyelonephritis

Pivotal phase III trial shows Tx potential of oral carbapenem for cUTI or acute pyelonephritis

For Asians with PCOS, ovarian reserve remains high even at advanced maternal age

For Asians with PCOS, ovarian reserve remains high even at advanced maternal age

JAK inhibitor exposure affects response to ritlecitinib for alopecia areata

JAK inhibitor exposure affects response to ritlecitinib for alopecia areata

Does antibiotic use prevent wound complications in episiotomy, second-degree tear?

Does antibiotic use prevent wound complications in episiotomy, second-degree tear?

Is high-dose IV push levetiracetam safe to administer?

Is high-dose IV push levetiracetam safe to administer?

High-dose flu vaccine extends benefit to adults aged 50–64 years

High-dose flu vaccine extends benefit to adults aged 50–64 years

Enfortumab vedotin plus pembrolizumab confers survival benefit in MIBC

Enfortumab vedotin plus pembrolizumab confers survival benefit in MIBC

Fixed-dose 4F-PCC safe, effective for FXal reversal in non-neurologic bleeds

Fixed-dose 4F-PCC safe, effective for FXal reversal in non-neurologic bleeds