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Paternal methotrexate use confers no teratogenic effects but may temporarily reduce fertility

04 Jul 2023

The periconceptional use of methotrexate among men does not contribute to an increase in the risk of congenital anomalies, preterm birth (PTB), and being small for gestational age (SGA), but it may lead to a temporary decrease in fertility, according to a study.

Paternal methotrexate use confers no teratogenic effects but may temporarily reduce fertility

04 Jul 2023

History of child abuse linked to female sexual dysfunction in midlife

01 Jul 2023

Women w an adverse childhood experience (ACE) are more likely to experience sexual dysfunction (SD) and sexual inactivity in midlife, irrespective of other factors that may influence female sexual function in adulthood, reveals a study.

History of child abuse linked to female sexual dysfunction in midlife

01 Jul 2023

COVID outcomes worse in polluted cities

01 Jul 2023 bởi

More evidence suggests that people exposed to more air pollution during the pandemic are at greater risk for COVID-19 infection, hospitalization, and death, but the exact mechanism behind the link is unknown.

COVID outcomes worse in polluted cities

01 Jul 2023

Original New Drug Application Approvals by US FDA (16-30 June 2023)

01 Jul 2023

New drug applications approved by US FDA as of 16-30 June 2023 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-30 June 2023)

01 Jul 2023

Another IBAT inhibitor makes its case in large PFIC trial

30 Jun 2023 bởi

The ileal bile acid transporter (IBAT) inhibitor maralixibat appears to quell itching and reduce serum bile acid concentration in children with progressive familial intrahepatic cholestasis (PFIC), while having a tolerable safety profile, according to data from the phase III MARCH-PFIC trial said to be the largest to date.

Another IBAT inhibitor makes its case in large PFIC trial

30 Jun 2023

Long-term data support teduglutide safety for SBS-IF

30 Jun 2023 bởi

In a pooled analysis of two long-term paediatric extension trials evaluating short bowel syndrome-associated intestinal failure (SBS-IF), the glucagon-like peptide-2 analogue teduglutide (TED) demonstrated a safety profile that aligned with previous data.

Long-term data support teduglutide safety for SBS-IF

30 Jun 2023

$Faecal transplant helps teens with refractory IBS$

Faecal transplant helps teens with refractory IBS

29 Jun 2023 bởi

For adolescents with treatment-refractory irritable bowel syndrome (IBS), faecal microbiota transplantation (FMT) is safe and beneficial, easing abdominal pain and improving health-related quality of life, according to a study presented at ESPGHAN 2023.

Faecal transplant helps teens with refractory IBS

29 Jun 2023

COVID-19 pandemic immensely impacts mental health in postnatal women

27 Jun 2023 bởi

A UK-based study demonstrated that the COVID-19 pandemic had an important negative impact on the mental health of postnatal women.

COVID-19 pandemic immensely impacts mental health in postnatal women

27 Jun 2023

New scorecard helps detect peanut allergy

27 Jun 2023 bởi

Paediatricians may have a new tool in a scorecard that could ably detect peanut allergy in infants with atopic dermatitis (AD).

New scorecard helps detect peanut allergy

27 Jun 2023

Dolutegravir safe, effective in paediatric HIV

24 Jun 2023

Use of dolutegravir (DTG) proves to be effective and safe in children and adolescents living with HIV (CALHIV) in low- and middle-income countries (LMICs), as shown in a study.

Dolutegravir safe, effective in paediatric HIV

24 Jun 2023

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Paternal methotrexate use confers no teratogenic effects but may temporarily reduce fertility

Paternal methotrexate use confers no teratogenic effects but may temporarily reduce fertility

History of child abuse linked to female sexual dysfunction in midlife

History of child abuse linked to female sexual dysfunction in midlife

COVID outcomes worse in polluted cities

COVID outcomes worse in polluted cities

Original New Drug Application Approvals by US FDA (16-30 June 2023)

Original New Drug Application Approvals by US FDA (16-30 June 2023)

Another IBAT inhibitor makes its case in large PFIC trial

Another IBAT inhibitor makes its case in large PFIC trial

Long-term data support teduglutide safety for SBS-IF

Long-term data support teduglutide safety for SBS-IF

Faecal transplant helps teens with refractory IBS

Faecal transplant helps teens with refractory IBS

COVID-19 pandemic immensely impacts mental health in postnatal women

COVID-19 pandemic immensely impacts mental health in postnatal women

New scorecard helps detect peanut allergy

New scorecard helps detect peanut allergy

Dolutegravir safe, effective in paediatric HIV

Dolutegravir safe, effective in paediatric HIV