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Efruxifermin misses mark in MASH-related compensated cirrhosis

10 Jun 2025

Treatment with the bivalent fibroblast growth factor 21 (FGF21) analogue efruxifermin falls short of improving fibrosis in patients with compensated cirrhosis caused by metabolic dysfunction–associated steatohepatitis (MASH), according to a phase 2b study.

Efruxifermin misses mark in MASH-related compensated cirrhosis

10 Jun 2025

Low-dose methotrexate of little benefit in knee OA with effusion-synovitis

09 Jun 2025

In patients with knee osteoarthritis (OA) with effusion, the use of low-dose methotrexate does not appear to relieve pain or reduce effusion-synovitis, as reported in a study.

Low-dose methotrexate of little benefit in knee OA with effusion-synovitis

09 Jun 2025

Single hyaluronic acid jab may be beneficial in managing vulvovaginal atrophy

09 Jun 2025 bởi

A single injection of cross-linked hyaluronic acid appears to help reduce vulvovaginal symptoms (VVA) and improve sexual dysfunction in postmenopausal women, as shown in a study.

Single hyaluronic acid jab may be beneficial in managing vulvovaginal atrophy

09 Jun 2025

Medication adherence helps lower CVD-related hospitalizations in older adults

09 Jun 2025 bởi

Adherence to medications contributes to a reduced risk of hospitalization due to cardiovascular disease (CVD) in older people with coronary heart disease (CHD), reports a Vietnam study.

Medication adherence helps lower CVD-related hospitalizations in older adults

09 Jun 2025

What drives prolonged recovery in older patients after rocuronium exposure?

09 Jun 2025

Older patients experience a slightly longer recovery time than their younger counterparts following administration of general anaesthesia, which is caused by an age-dependent increase in tissue uptake, a recent study has shown.

What drives prolonged recovery in older patients after rocuronium exposure?

09 Jun 2025

Efruxifermin reduces fibrosis in MASH cirrhosis

09 Jun 2025 bởi

The long-acting, bivalent fibroblast growth factor 21 analogue efruxifermin reduced fibrosis at 96 weeks in patients with compensated cirrhosis due to metabolic dysfunction-associated steatohepatitis (MASH) in the phase 2b SYMMETRY trial.

Efruxifermin reduces fibrosis in MASH cirrhosis

09 Jun 2025

Prenatal triptan exposure unlikely to harm neurodevelopmental outcomes in children

08 Jun 2025 bởi

Maternal use of the migraine drug triptans before or during pregnancy does not appear to put infants at risk of developing neurodevelopmental disorders, according to a study.

Prenatal triptan exposure unlikely to harm neurodevelopmental outcomes in children

08 Jun 2025

GLP1-RA treatment not harmful to mental health

08 Jun 2025

In the treatment of patients with overweight/obesity and/or diabetes, glucagon-like peptide 1 receptor agonists (GLP1-RAs) do not increase the risk of psychiatric adverse events or worsen depressive symptoms but rather confer improvements in quality of life (QOL) and eating behaviour, according to the results of a meta-analysis.

GLP1-RA treatment not harmful to mental health

08 Jun 2025

Multiple antibiotic exposures in early life may have long-term respiratory consequences

07 Jun 2025

Preterm infants with multiple episodes of antibiotic exposure prenatally have a higher likelihood of having impaired lung function at early school age, as shown in a study.

Multiple antibiotic exposures in early life may have long-term respiratory consequences

07 Jun 2025

Gemcitabine for IR-NMIBC tied to more recurrence vs BCG

06 Jun 2025 bởi

Treatment-naive patients with immediate-risk (IR) nonmuscle-invasive bladder cancer (NMIBC) who received gemcitabine appear to have greater recurrence risk than those given Bacillus Calmette-Guerin (BCG). Both treatments, however, are effective against disease progression.

Gemcitabine for IR-NMIBC tied to more recurrence vs BCG

06 Jun 2025

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Efruxifermin misses mark in MASH-related compensated cirrhosis

Efruxifermin misses mark in MASH-related compensated cirrhosis

Low-dose methotrexate of little benefit in knee OA with effusion-synovitis

Low-dose methotrexate of little benefit in knee OA with effusion-synovitis

Single hyaluronic acid jab may be beneficial in managing vulvovaginal atrophy

Single hyaluronic acid jab may be beneficial in managing vulvovaginal atrophy

Medication adherence helps lower CVD-related hospitalizations in older adults

Medication adherence helps lower CVD-related hospitalizations in older adults

What drives prolonged recovery in older patients after rocuronium exposure?

What drives prolonged recovery in older patients after rocuronium exposure?

Efruxifermin reduces fibrosis in MASH cirrhosis

Efruxifermin reduces fibrosis in MASH cirrhosis

Prenatal triptan exposure unlikely to harm neurodevelopmental outcomes in children

Prenatal triptan exposure unlikely to harm neurodevelopmental outcomes in children

GLP1-RA treatment not harmful to mental health

GLP1-RA treatment not harmful to mental health

Multiple antibiotic exposures in early life may have long-term respiratory consequences

Multiple antibiotic exposures in early life may have long-term respiratory consequences

Gemcitabine for IR-NMIBC tied to more recurrence vs BCG

Gemcitabine for IR-NMIBC tied to more recurrence vs BCG