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Maternal obesity may elevate bile acids in breast milk

24 Apr 2026

Maternal obesity appears to increase bile acid (BA) levels in breast milk, which may have implications for neonatal digestion, maturation, and health.

Maternal obesity may elevate bile acids in breast milk

24 Apr 2026

GLP-1RAs offer histologic benefits in MASH without fibrosis progression

23 Apr 2026 bởi

Treatment with glucagon-like peptide-1 receptor agonists (GLP-1RAs), such as semaglutide and liraglutide, improves histologic outcomes in patients with biopsy-confirmed metabolic dysfunction-associated steatohepatitis (MASH) without compromising safety, reports a Singapore study.

GLP-1RAs offer histologic benefits in MASH without fibrosis progression

23 Apr 2026

MM780G system effectively maintains glycaemic control on no-bolus days

23 Apr 2026 bởi

A real-world analysis shows effective glycaemic control with the MiniMed 780G (MM780G) system—an advanced automated insulin delivery (AID) system with bolus autocorrection every 5 min—in users on no-bolus days, with more users achieving glycaemic goals when the recommended optimal settings (ROS) were used.

MM780G system effectively maintains glycaemic control on no-bolus days

23 Apr 2026

Hybrid obesity care delivers substantial benefits in real-world patients in SG

20 Apr 2026 bởi

A hybrid obesity care that combines physician-directed glucagon-like peptide-1 receptor agonist (GLP-1 RA) treatment and lifestyle coaching via a mobile health app yields meaningful and sustained improvements in weight and metabolic parameters in a real-world setting, as shown in a local study.

Hybrid obesity care delivers substantial benefits in real-world patients in SG

20 Apr 2026

EUS-RFA eases symptoms in patients with insulinomas

20 Apr 2026

Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) offers a minimally invasive resolution of symptoms in patients with a suspicion of insulinomas and has a favourable safety profile relative to surgery, according to a study. However, its long-term efficacy warrants further investigation.

EUS-RFA eases symptoms in patients with insulinomas

20 Apr 2026

MACS patients suffer sleep impairment similar to those with Cushing syndrome

20 Apr 2026

Patients with mild autonomous cortisol secretion (MACS) may experience poor sleep quality comparable to those with Cushing syndrome (CS), reports a study. Notably, sleep impairment appears to be more common among younger women with higher clinical MACS severity.

MACS patients suffer sleep impairment similar to those with Cushing syndrome

20 Apr 2026

SURPASS-CVOT: Tirzepatide better than dulaglutide for cardiorenal outcomes

17 Apr 2026 bởi

Treatment with tirzepatide, a dual GLP-1* and GIP** agonist, significantly improves cardiovascular and renal outcomes in patients with diabetes and atherosclerotic cardiovascular disease (ASCVD) compared with dulaglutide, according to a post hoc analysis of the SURPASS-CVOT trial presented at ACC.26.

SURPASS-CVOT: Tirzepatide better than dulaglutide for cardiorenal outcomes

17 Apr 2026

MetS risk higher in children with primary hypertension

16 Apr 2026

Children with hypertension, particularly those with primary hypertension, are vulnerable to developing metabolic syndrome (MetS), reveals a study.

MetS risk higher in children with primary hypertension

16 Apr 2026

Can prednisolone be used in place of hydrocortisone in adrenal insufficiency?

13 Apr 2026 bởi

The use of once-daily, low-dose prednisolone for glucocorticoid replacement in adrenal insufficiency yields substantial improvements in bone turnover and cardiometabolic health markers compared with multiple-dose hydrocortisone, according to the results of a crossover randomized clinical trial.

Can prednisolone be used in place of hydrocortisone in adrenal insufficiency?

13 Apr 2026

Semaglutide confers ASCVD risk factor benefits in high-risk patients

11 Apr 2026

Treatment with semaglutide yields early and sustained improvements in multiple atherosclerotic cardiovascular disease (ASCVD) factors in high-risk patients with type 2 diabetes (T2D) and ASCVD and/or chronic kidney disease (CKD), according to a post hoc analysis of the SOUL trial.

Semaglutide confers ASCVD risk factor benefits in high-risk patients

11 Apr 2026

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Maternal obesity may elevate bile acids in breast milk

Maternal obesity may elevate bile acids in breast milk

GLP-1RAs offer histologic benefits in MASH without fibrosis progression

GLP-1RAs offer histologic benefits in MASH without fibrosis progression

MM780G system effectively maintains glycaemic control on no-bolus days

MM780G system effectively maintains glycaemic control on no-bolus days

Hybrid obesity care delivers substantial benefits in real-world patients in SG

Hybrid obesity care delivers substantial benefits in real-world patients in SG

EUS-RFA eases symptoms in patients with insulinomas

EUS-RFA eases symptoms in patients with insulinomas

MACS patients suffer sleep impairment similar to those with Cushing syndrome

MACS patients suffer sleep impairment similar to those with Cushing syndrome

SURPASS-CVOT: Tirzepatide better than dulaglutide for cardiorenal outcomes

SURPASS-CVOT: Tirzepatide better than dulaglutide for cardiorenal outcomes

MetS risk higher in children with primary hypertension

MetS risk higher in children with primary hypertension

Can prednisolone be used in place of hydrocortisone in adrenal insufficiency?

Can prednisolone be used in place of hydrocortisone in adrenal insufficiency?

Semaglutide confers ASCVD risk factor benefits in high-risk patients

Semaglutide confers ASCVD risk factor benefits in high-risk patients