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BMI and glycaemic status significantly affect CV risk in patients treated with anthracyclines

24 Jun 2025 bởi

A retrospective cohort study of >11,000 Hong Kong patients who initiated anthracycline-based chemotherapy found that both body-mass index (BMI) and glycaemic status significantly affect cardiovascular (CV) risks, with the highest risk observed in those with concurrent obesity and diabetes/prediabetes.

BMI and glycaemic status significantly affect CV risk in patients treated with anthracyclines

24 Jun 2025

Long-term data solidify partial-breast RT as standard of care in low-risk early breast cancer

23 Jun 2025 bởi

In patients with low-risk, early-stage breast cancer who have undergone breast-conserving surgery, partial-breast radiotherapy (RT) is as safe and efficacious as whole-breast RT, according to 10-year data from the phase III IMPORT LOW trial.

Long-term data solidify partial-breast RT as standard of care in low-risk early breast cancer

23 Jun 2025

Penpulimab extends survival in R/M nasopharyngeal carcinoma

23 Jun 2025 bởi

The use of penpulimab, in combination with gemcitabine and cisplatin or carboplatin, as first-line treatment for recurrent or metastatic (R/M) nasopharyngeal carcinoma (NPC) provides statistically significant and clinically meaningful benefit, according to a study presented at AACR 2025.

Penpulimab extends survival in R/M nasopharyngeal carcinoma

23 Jun 2025

Cabozantinib plus atezolizumab improves PFS in mCRPC after progression on ARPI

20 Jun 2025

In the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) with extrapelvic soft-tissue metastases that has progressed on an androgen receptor pathway inhibitor (ARPI), the combination of cabozantinib plus atezolizumab appears to prolong progression-free survival (PFS), according to data from the open-label phase 3 CONTACT-02 trial.

Cabozantinib plus atezolizumab improves PFS in mCRPC after progression on ARPI

20 Jun 2025

Insulinemic lifestyle pattern ups risk of endometrial cancer

14 Jun 2025

A lifestyle pattern with higher insulinemic potential may predispose an individual to endometrial cancer (EC), suggests a study.

Insulinemic lifestyle pattern ups risk of endometrial cancer

14 Jun 2025

Chemo-free triplet regimen shows antitumour activity in HR+, HER2+ breast cancer

14 Jun 2025

Treatment with the combination of zanidatamab plus palbociclib and fulvestrant is safe and demonstrates promising antitumour activity in patients with HR-positive, HER2-positive advanced or metastatic breast cancer, according to a phase IIa study.

Chemo-free triplet regimen shows antitumour activity in HR+, HER2+ breast cancer

14 Jun 2025

Ultrasensitive ctDNA detection predicts breast cancer relapse

13 Jun 2025 bởi

A molecular residual disease (MRD) assay powered by whole genome sequencing (WGS) successfully detects breast cancer relapse, improving lead times for circulating tumour DNA (ctDNA) detection years ahead of clinical recurrence based on imaging.

Ultrasensitive ctDNA detection predicts breast cancer relapse

13 Jun 2025

Healthy lifestyle behaviours protective against breast cancer in postmenopausal women

13 Jun 2025

Postmenopausal women who engage in healthy lifestyle behaviours appear to have a reduced risk of breast cancer, regardless of race and ethnicity and hormone receptor status, according to a study.

Healthy lifestyle behaviours protective against breast cancer in postmenopausal women

13 Jun 2025

PFS, OS in unresectable HCC prolonged with anlotinib plus penpulimab

12 Jun 2025

In the treatment of patients with unresectable hepatocellular carcinoma (HCC), anlotinib plus pepulimab appears to significantly increase progression-free survival (PFS) and overall survival (OS) compared with sorafenib, as shown in the results of the phase III APOLLO study conducted in China.

PFS, OS in unresectable HCC prolonged with anlotinib plus penpulimab

12 Jun 2025

Low-carb, animal fat/protein-heavy diet poses increased bladder cancer risk

12 Jun 2025 bởi

A low-carbohydrate diet (LCD), particularly when its fat and protein sources are predominantly animal-based, may contribute to increased risk of bladder cancer among Chinese Singaporeans, according to new research.

Low-carb, animal fat/protein-heavy diet poses increased bladder cancer risk

12 Jun 2025

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BMI and glycaemic status significantly affect CV risk in patients treated with anthracyclines

BMI and glycaemic status significantly affect CV risk in patients treated with anthracyclines

Long-term data solidify partial-breast RT as standard of care in low-risk early breast cancer

Long-term data solidify partial-breast RT as standard of care in low-risk early breast cancer

Penpulimab extends survival in R/M nasopharyngeal carcinoma

Penpulimab extends survival in R/M nasopharyngeal carcinoma

Cabozantinib plus atezolizumab improves PFS in mCRPC after progression on ARPI

Cabozantinib plus atezolizumab improves PFS in mCRPC after progression on ARPI

Insulinemic lifestyle pattern ups risk of endometrial cancer

Insulinemic lifestyle pattern ups risk of endometrial cancer

Chemo-free triplet regimen shows antitumour activity in HR+, HER2+ breast cancer

Chemo-free triplet regimen shows antitumour activity in HR+, HER2+ breast cancer

Ultrasensitive ctDNA detection predicts breast cancer relapse

Ultrasensitive ctDNA detection predicts breast cancer relapse

Healthy lifestyle behaviours protective against breast cancer in postmenopausal women

Healthy lifestyle behaviours protective against breast cancer in postmenopausal women

PFS, OS in unresectable HCC prolonged with anlotinib plus penpulimab

PFS, OS in unresectable HCC prolonged with anlotinib plus penpulimab

Low-carb, animal fat/protein-heavy diet poses increased bladder cancer risk

Low-carb, animal fat/protein-heavy diet poses increased bladder cancer risk