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The next-generation selective Bruton tyrosine kinase inhibitor zanubrutinib appears to be safe and effective in the treatment of patients with relapsed/refractory marginal zone lymphoma, as evidenced by high rates of objective response and complete response, according to data from the phase II MAGNOLIA (BGB-3111–214) study.

Novel BTK inhibitor as good as established therapies for refractory marginal zone lymphoma

Prenatal nicotine, cannabis exposures not a hazard to neurodevelopmental outcomes

Neither prenatal nicotine nor cannabis exposure adversely affects offspring intelligence quotient (IQ), a study reports. However, cannabis exposure appears to have unfavourable effects on attention in early childhood.

Prenatal nicotine, cannabis exposures not a hazard to neurodevelopmental outcomes

Evinacumab reduces LDL-C levels in homozygous FH

09 Dec 2021 bởi

Treatment with evinacumab, an angiopoietin-like protein 3 (ANGPTL3) inhibitor, reduces low-density lipoprotein cholesterol (LDL-C) levels in adolescents and adults with homozygous familial hypercholesterolaemia (FH), according to a study presented at AHA 2021.

Evinacumab reduces LDL-C levels in homozygous FH

Inferior vena cava filters safely reduce pulmonary embolism risk in VTE

The use of inferior vena cava filters appears to effectively reduce the risk of pulmonary embolism (PE) and PE-related and all-cause deaths in patients with venous thromboembolism (VTE), reports a recent meta-analysis.

Inferior vena cava filters safely reduce pulmonary embolism risk in VTE

08 Dec 2021

Inflammatory food may up dementia risk

Following a diet with high pro-inflammatory potential is associated with an increased risk of developing dementia, suggest data from the HELIAD* study.

Inflammatory food may up dementia risk

Short-course, high-dose gatifloxacin gets a pass in multidrug-resistant TB with caveat

A short-term treatment regimen based on high-dose gatifloxacin appears to be effective against multidrug- or rifampicin-resistant tuberculosis (TB) but at the cost of increased severe adverse drug reactions, as shown in a study.

Short-course, high-dose gatifloxacin gets a pass in multidrug-resistant TB with caveat

08 Dec 2021

Botox injection achieves successful motor alignment in patients with strabismus

Extraocular muscle injection of botulinum toxin type A (BTXA) results in a high rate of successful motor alignment, which is similar to that achieved following eye muscle surgery for nonparalytic, nonrestrictive horizontal strabismus, reports a recent study.

Botox injection achieves successful motor alignment in patients with strabismus

Ixekizumab effective for difficult-to-treat psoriatic arthritis

The monoclonal antibody ixekizumab improved the signs and symptoms of psoriatic arthritis (PsA) in PsA patients with inadequate response to one or two tumour necrosis factor inhibitors (TNFis), suggests results from a post hoc subanalysis of the SPIRIT-P2 trial.

Ixekizumab effective for difficult-to-treat psoriatic arthritis

08 Dec 2021

Air pollution responsible for thousands of deaths yearly: study

Despite significant progress in controlling air pollution, it remains an urgent public health problem, according to a recent European study, which found that more than 300,000 deaths in the region could be attributed to air pollution in 2019.

Air pollution responsible for thousands of deaths yearly: study

Breast cancer: Dense breasts may spell trouble for menopausal women