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Ipatasertib shows promising activity against AKT1E17K-mutant tumours

04 Dec 2025

Treatment with the pan-AKT inhibitor ipatasertib appears to induce response in patients with tumours harbouring AKT1E17K mutations, according to a study.

Ipatasertib shows promising activity against AKT1E17K-mutant tumours

04 Dec 2025

$Pancreatic cancer: What’s the optimal Tx sequence for hypofractionated proton beam therapy with simultaneous integrated boost$

Pancreatic cancer: What’s the optimal Tx sequence for hypofractionated proton beam therapy with simultaneous integrated boost?

04 Dec 2025 bởi

Hypofractionated proton beam therapy with simultaneous integrated boost technique (SIB-PBT) can be used as a safe and effective local treatment for locally advanced pancreatic cancer (LAPC), particularly in patients with stable disease (SD) following induction chemotherapy, according to findings from the largest cohort to date presented at PTCOG-AO 2025.

Pancreatic cancer: What’s the optimal Tx sequence for hypofractionated proton beam therapy with simultaneous integrated boost?

04 Dec 2025

Original New Drug Application Approvals by US FDA (16-31 October 2025)

02 Dec 2025

New drug applications approved by US FDA as of 16-31 October 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-31 October 2025)

02 Dec 2025

Dietary fibre intake may lessen bowel-related symptoms in CRC survivors

30 Nov 2025

For survivors of colorectal cancer (CRC), consuming more fibre in their daily diet helps reduce bowel-related symptoms, according to a study.

Dietary fibre intake may lessen bowel-related symptoms in CRC survivors

30 Nov 2025

ICI-induced endocrinopathies: Patient education, regular monitoring, and early appropriate management important

28 Nov 2025 bởi

Regular monitoring and recognizing tell-tale signs upon first presentation are important in managing endocrine immune-related adverse events (irAEs) induced by immune checkpoint inhibitors (ICIs), for optimized cancer treatment outcomes, stressed Dr David Lui from the University of Hong Kong, at the 8^th Endocrinology, Diabetes & Metabolism Hong Kong Annual Meeting (EDM HK 2025).

ICI-induced endocrinopathies: Patient education, regular monitoring, and early appropriate management important

28 Nov 2025

Carotenoid intake may lower CRC risk

27 Nov 2025 bởi

Total and selected carotenoids are inversely associated with the risk of colorectal cancer (CRC), suggests a recent study.

Carotenoid intake may lower CRC risk

27 Nov 2025

PBP superior to pericardiocentesis in reducing malignant pericardial effusion recurrence

27 Nov 2025 bởi

Percutaneous balloon pericardiotomy (PBP) significantly reduces recurrence of malignant pericardial effusion (MPE) by 85 percent compared with pericardiocentesis (PC), according to the randomized controlled PMAP trial conducted by a multispecialty team of researchers from the Chinese University of Hong Kong (CUHK).

PBP superior to pericardiocentesis in reducing malignant pericardial effusion recurrence

27 Nov 2025

Osimertinib linked to cardiac events in NSCLC patients

26 Nov 2025 bởi

Patients with non-small cell lung cancer (NSCLC) treated with osimertinib have a higher risk of QT prolongation, reduced ejection fraction, and high-grade cardiac failure than those who received placebo or other standard therapies, reports a study.